Method of treatment of a pulmonary embolism

Patent metadata

Field	Value
Publication number	US-12415053-B2
Application number	US-202318451968-A
Country	US
Kind code	B2
Filing date	Aug 18, 2023
Priority date	Apr 15, 2015
Publication date	Sep 16, 2025
Grant date	Sep 16, 2025

Abstract

An apparatus and methods for use are provided, where the apparatus includes: (a) a first catheter having a proximal end and a distal end, and wherein a distal portion of the first catheter includes a first one or more outlets, (b) a first tubular housing having a proximal end and a distal end, wherein the first tubular housing is coupled to the first catheter proximal to the at least one first outlet, (c) one or more pressure sensors coupled to the distal end of the first tubular housing, and (d) a second catheter having a proximal end and a distal end, wherein a distal portion of the second catheter includes a second one or more outlets, and wherein the distal end of the second catheter is configured to be positioned substantially within one of (i) the first catheter or (ii) a second tubular housing coupled to one or more of the first catheter and the first tubular housing, when the second catheter is in a first position.

First claim

The invenion claimed is:

1. A method comprising:
positioning a distal end of a first catheter into a first branch of a pulmonary artery, wherein the distal end of the first catheter includes a first plurality of outlets;
positioning a distal end of a second catheter into a second branch of the pulmonary artery, wherein the distal end of the second catheter includes a second plurality of outlets; wherein the second catheter is moveable with respect to the first catheter from a deployment position in which the distal end of the second catheter is positioned within a tubular housing to a treatment position in which the distal end of the second catheter extends out of the tubular housing and is positioned in the second branch of the pulmonary artery; and
advancing a treatment solution out of both the first plurality of outlets of the first catheter and into the first branch of the pulmonary artery;
advancing a treatment solution out of the second plurality of outlets of the second catheter and into the second branch of the pulmonary artery;
determining, via one or more pressure sensors, a blood pressure is less than a threshold value corresponding to a normal blood pressure range; and
in response to the determination that the blood pressure is less than the threshold value, removing the first catheter and the second catheter from the pulmonary artery.

2. The method of claim 1 , further comprising:
after positioning the distal end of the first catheter into the first branch of the pulmonary artery and after positioning the distal end of the second catheter into the second branch of the pulmonary artery, monitoring a blood pressure via the one or more pressure sensors; and
after advancing the treatment solution out of the first plurality of outlets of the first catheter and the second plurality of outlets of the second catheter, monitoring the blood pressure via the one or more pressure sensors.

3. The method of claim 1 , further comprising:
inflating a balloon coupled to the distal end of the first catheter; and
advancing the distal end of the first catheter, via the balloon, from an inferior vena cava to a right ventricle, through a pulmonary valve to the pulmonary artery.

4. The method of claim 1 , further comprising:
determining a first blood pressure, via one or more pressure sensors at a first time;
determining a second blood pressure, via the one or more pressure sensors at a second time later than the first time; and
comparing the first blood pressure to the second blood pressure to determine a change in blood pressure.

5. The method of claim 1 , further comprising:
determining at a first time, via the one or more pressure sensors, a blood pressure is greater than the threshold value corresponding to a normal blood pressure range; and
in response to the determination that the blood pressure is greater than the threshold value,
activating a pump to advance the treatment solution out of the first plurality of outlets of the first catheter and the second plurality of outlets of the second catheter.

6. The method of claim 5 , further comprising:
determining at a second time later than the first time, via the one or more pressure sensors, a blood pressure is less than the threshold value; and
in response to the determination that the blood pressure is less than the threshold value, deactivating the pump.

Assignees

• Sanford Health

Inventors

• Kelly Patrick W

Classifications

• A61M2230/30

  Blood pressure (A61M2230/04 takes precedence) · CPC title

• A61M2205/3379

  Masses, volumes, levels of fluids in reservoirs, flow rates · CPC title

• A61M2025/0002

  with a pressure sensor at the distal end · CPC title

• A61M2005/1726

  the body parameters being measured at, or proximate to, the infusion site · CPC title

• A61M25/10

  Balloon catheters ({A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02;} inflatable balloons for placing stents or stent-grafts A61F2/958 {; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00}) · CPC title