Biodegradable single-phase cohesive hydrogel
US-2024335587-A1 · Oct 10, 2024 · US
US12414909B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12414909-B2 |
| Application number | US-202017772676-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 27, 2020 |
| Priority date | Oct 28, 2019 |
| Publication date | Sep 16, 2025 |
| Grant date | Sep 16, 2025 |
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A method for the preparation of a gelled polysaccharide foam, which includes the following steps: (a) the preparation of a mixture including at least one solubilized polysaccharide chosen from alginates, pectic substances, carrageenans, and mixtures thereof, at least one solvent of the polysaccharide, at least one ionic crosslinking agent of the polysaccharide, the crosslinking agent being not available, optionally a plasticizer soluble into the solvent, optionally a surfactant, and optionally an additive, (b) foaming and gelling the mixture prepared at step (a) by incorporating a pH modifying gas, and (c) optionally drying the gelled foam obtained at step (b). Also, the gelled foam obtained from such a method as well as the uses thereof.
Opening claim text (preview).
The invention claimed is: 1. A method for the preparation of a gelled polysaccharide foam comprising the following steps: (a) the preparation of a mixture comprising: at least one solubilized polysaccharide chosen from alginates, pectic substances, carrageenans, and mixtures thereof at least one solvent of said polysaccharide, at least one ionic crosslinking agent of said polysaccharide, the crosslinking agent being not available, optionally at least one plasticizer soluble into said solvent, optionally at least one surfactant, and optionally at least one additive, (b) foaming and gelling said mixture prepared at step (a) by incorporating a pH modifying gas, and (c) optionally drying the gelled foam obtained at step (b). 2. The method according to claim 1 , wherein the at least one solubilized polysaccharide is an alginate. 3. The method according to claim 1 , wherein the at least one solubilized polysaccharide is present in an amount of 0.5% to 10% by weight, relative to the total weight of the mixture. 4. The method according to claim 1 , wherein the at least one ionic crosslinking agent is at least one polyvalent cation. 5. The method according to claim 1 , wherein the at least one ionic crosslinking agent is a bivalent ion in chelated form. 6. The method according to claim 1 , wherein the at least one ionic crosslinking agent is present in an amount of 0.1% to 15% by weight, relative to the total weight of the mixture. 7. The method according to claim 1 , wherein the at least one solvent is an inorganic solvent. 8. The method according to claim 1 , wherein the at least one solvent is present in an amount of 50% to 99% by weight, relative to the total weight of the mixture. 9. The method according to claim 1 , wherein the at least one surfactant is a nonionic or anionic surfactant. 10. The method according to claim 1 , wherein the at least one surfactant is present in an amount of 0.01% to 10% by weight, relative to the total weight of the mixture. 11. The method according to claim 1 , wherein the at least one additive is an active agent. 12. The method according to claim 1 , wherein the at least one additive is present in an amount of 0.5% to 20% by weight, relative to the total weight of the mixture. 13. The method according to claim 1 , wherein the pH-modifying gas is an acid gas. 14. The method according to claim 1 , wherein step (b) is implemented by incorporating a mixture of said acid gas with an inert gas. 15. A gelled polysaccharide foam obtained from the method according to claim 1 . 16. A method of controlling release of active agents in food or cosmetics field, comprising adding a polysaccharide gel foam according to claim 15 to a food or cosmetic. 17. A method for treating wounds comprising applying to the wounds a polysaccharide gel foam according to claim 15 . 18. The method for treating wounds according to claim 17 , wherein the wounds are selected from the group consisting of cavity wounds, venous ulcers, diabetic foot ulcers, and pressure ulcers. 19. The method according to claim 1 , wherein the ionic crosslinking agent is at least one bivalent cation or trivalent cation. 20. The method according to claim 1 , wherein the pH-modifying gas is an acid gas selected from the group consisting of carbon dioxide, sulfur dioxide, nitrogen oxide, and a mixture thereof.
Preparations for care of the skin · CPC title
Thickener, Thickening system · CPC title
Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin · CPC title
Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title
Foaming or whipping · CPC title
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