Bis-benzylidine piperidone proteasome inhibitor with anticancer activity
US-9913834-B2 · Mar 13, 2018 · US
Anti-cancer spirocyclic-guanidine compounds and uses thereof
US12410141B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12410141-B2 |
| Application number | US-202117925923-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 18, 2021 |
| Priority date | May 18, 2020 |
| Publication date | Sep 9, 2025 |
| Grant date | Sep 9, 2025 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The invention of the instant application discloses spirocyclic guanidine compounds of general formula (I), shown below, and their use in methods of treating cancer
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound selected from the group consisting of, 2. A method of treating cancer comprising administering a compound of claim 1 , wherein the cancer is selected from the group consisting of multiple myeloma, ovarian cancer, cervical cancer, breast cancer, liver cancer, and colon cancer. 3. The method of claim 2 , wherein the cancer is a liquid cancer or a solid cancer. 4. The method of claim 3 wherein the cancer is a solid cancer.
Assignees
Inventors
Classifications
Antineoplastic agents · CPC title
Spiro-condensed · CPC title
containing carbocyclic rings other than six-membered · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
- C07D221/20Primary
Spiro-condensed ring systems · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US12410141B2 cover?
- The invention of the instant application discloses spirocyclic guanidine compounds of general formula (I), shown below, and their use in methods of treating cancer
- Who is the assignee on this patent?
- Univ Johns Hopkins
- What technology area does this patent fall under?
- Primary CPC classification C07D221/20. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 09 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).