Systems and methods for correcting photic phenomenon from an intraocular lens and using refractive index writing

Patent metadata

Field	Value
Publication number	US-12409028-B2
Application number	US-202318171341-A
Country	US
Kind code	B2
Filing date	Feb 18, 2023
Priority date	Apr 5, 2019
Publication date	Sep 9, 2025
Grant date	Sep 9, 2025

Abstract

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon.

First claim

What is claimed is:

1. A method for improving vision of a subject having an implanted intraocular lens (IOL), the method comprising:
determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and
applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon, wherein the IOL is a diffractive IOL or a refractive IOL and compensating for the photic phenomena comprises at least partially compensating for a phase delay associated with the phase shift.

2. The method of claim 1 , wherein applying the plurality of laser pulses comprises applying a plurality of focused laser pulses, according to a predetermined pattern, to at least one selected area of the IOL to produce, by the refractive index writing on the IOL, the phase shift.

3. The method of claim 1 or 2 , wherein the photic phenomenon is a halo, a starburst, or a glare.

4. The method of claim 1 , wherein the phase shift in the IOL to compensate for the photic phenomenon comprises a radially dependent phase shift.

5. The method of claim 1 , further comprising verifying correction of the at least one photic phenomenon following the application of the laser pulses.

6. The method of claim 5 , wherein verifying the correction incorporates subject feedback provided following the application of the laser pulses.

7. The method of claim 1 , wherein the determining at least one photic phenomena comprises measuring and mapping the photic phenomenon experienced by the subject.

8. The method of claim 1 , further comprising determining a phase delay associated with the phase shift to compensate for at least one photic phenomena comprises simulations of the optimal higher order aberrations induction based on pupil size analysis.

9. The method of claim 8 , wherein the simulations of the optimal higher order aberrations induction are based on subject response to photic phenomena.

10. The method of claim 1 , wherein compensating for the photic phenomenon comprises refractive optimization, apodization, partial apodization, or profile reversion.

11. The method of claim 10 , wherein the refractive optimization comprises correcting, by the refractive index writing, defocus, astigmatism, or higher order aberrations.

12. The method of claim 10 , wherein the apodization comprises eliminating, by inverted phase delay, the diffractive or refractive IOL design in an outer part of the lens.

13. The method of claim 12 , wherein apodization phase delay is determined using feedback from the subject relating to experiencing the photic phenomena.

14. The method of claim 12 , wherein the apodization further comprises maintaining a central part of the diffractive design, wherein the peripheral part is defined based on the specific photic phenomenon experienced by the subject.

15. The method of claim 10 , wherein the partial apodization comprises modifying the percentage of light distributed between different foci of a multifocal IOL in an outer part of the lens.

16. The method of claim 10 , wherein the profile reversion comprises eliminating the full diffractive profile of the IOL.

17. The method of claim 11 , wherein correcting higher order aberrations comprises performing an iterative, closed-loop correction process including:
measuring the higher order aberrations;
determining a target higher order aberration correction that exhibits one or more of:
full correction of at least one of the higher order aberrations of the subject;
partial correction of at least one of the higher order aberrations of the subject; or
induction of at least one higher order aberration based on the measuring;

applying, by refractive index writing, a plurality of pulses of radiation to one or more selected areas of the IOL, the plurality of pulses being configured to produce a target higher order aberration correction profile on the IOL;
(a) determining if the produced correction profile meets the target higher order aberration correction profile;
(b) responsive to determining that the produced correction profile does not meet the target higher order aberration correction profile:
(i) measuring the difference between the higher order aberrations profile of the IOL after the prior application of the plurality of pulses of radiation and the target higher order aberrations correction and, based on the measured difference, calculating a profile to achieve the target higher order aberration correction,
(ii) applying, by refractive index writing, a next plurality of pulses of radiation to the IOL, wherein the configuration of the pulses of radiation is modified based on the measured difference, and

repeating the steps (i) and (ii) until the produced higher order aberration correcting profile meets the determined target higher order aberration correction.

18. A method for improving vision of a subject having an implanted intraocular lens (IOL), the method comprising:
determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and
applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon; and
determining a phase delay associated with the phase shift to compensate for at least one photic phenomena comprises simulations of the optimal higher order aberrations induction based on pupil size analysis.

19. A method for improving vision of a subject having an implanted intraocular lens (IOL), the method comprising:
determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and
applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon; and
determining a phase delay associated with the phase shift to compensate for at least one photic phenomena comprises simulations of the optimal higher order aberrations induction based on pupil size analysis, wherein the simulations of the optimal higher order aberrations induction are based on subject response to photic phenomena.

Assignees

• Amo Groningen Bv

Inventors

• Rosen Robert
• Gounou Franck Emmanuel
• Canovas Vidal Carmen
• Alarcon Heredia Aixa

Classifications

• A61F2009/00848

  based on wavefront · CPC title

• A61F9/008

  using laser · CPC title

• A61B2017/00181

  Means for setting or varying the pulse energy · CPC title

• A61F2009/00842

  Permanent Structural Change [PSC] in index of refraction; Limit between ablation and plasma ignition · CPC title

• A61F2/1627 Primary

  for changing index of refraction, e.g. by external means or by tilting · CPC title