Lead for applying electrical stimulation to body organ, and electrode system using same

Patent metadata

Field	Value
Publication number	US-12403301-B2
Application number	US-202117921960-A
Country	US
Kind code	B2
Filing date	Apr 1, 2021
Priority date	Apr 28, 2020
Publication date	Sep 2, 2025
Grant date	Sep 2, 2025

Abstract

A lead implanted in a body to apply electrical stimulation to body organs includes an electrode wire having one end provided as an insertion portion to be inserted into a body and another end provided as an interface portion for connection with an external device; a first electrode in the insertion portion to transmit electrical stimulation to body organs; a second electrode on the interface portion to receive electrical stimulation applied from outside; a signal line that interconnects the first electrode and second electrode to transmit electrical stimulation received by the second electrode to the first electrode; and a ring member that covers the first electrode and has an opening for exposing the first electrode in a portion of a circumferential direction, and is mounted to be movable in a longitudinal or circumferential direction with respect to the electrode wire by an external force to adjust an exposure position of the first electrode.

First claim

The invention claimed is:

1. A lead implanted in a body to apply electrical stimulation to body organs, the lead comprising:
an electrode wire having one end provided as an insertion portion to be inserted into a body and another end provided as an interface portion for connection with an external device;
a first electrode in the insertion portion to transmit electrical stimulation to body organs;
a second electrode on the interface portion to receive electrical stimulation applied from outside;
a signal line that interconnects the first electrode and the second electrode to transmit electrical stimulation received by the second electrode to the first electrode; and
a ring member disposed on the electrode wire that covers the first electrode and has an opening that exposes the first electrode in a portion of a circumferential direction, and is mounted on the electrode wire to be movable in a longitudinal or circumferential direction with respect to the electrode wire by an external force to adjust an exposure position of the first electrode through the opening,
wherein the ring member is comprised of a plurality of ring members each comprised of an insulating material that prevents exposure of electrical stimulation therethrough and arranged adjacent to each other in a longitudinal direction at the insertion portion of the electrode wire,
wherein each of the plurality of ring members is independently rotatable by at least one of a manual operation member or a controller to selectively adjust its position in the circumferential direction and the position of the opening to expose the first electrode through the opening of each of the plurality of ring members and to provide selective areas of the applied electrical stimulation from the first electrode through the openings.

2. The lead of claim 1 , wherein each of the plurality of ring members is movable with respect to the electrode wire by the controller applying a magnetic force to attract and couple at least one ring member of the plurality of ring members to a portion of the controller and as the portion of the controller is one of moved or rotated in one of the longitudinal direction or the circumferential direction with respect to the electrode wire the at least one ring member is moved or rotated in the direction.

3. The lead of claim 1 , wherein a gap between the openings of each of the plurality of ring members is adjusted by an external force applied to the manual operation member.

4. The lead of claim 1 , wherein the first electrode extends obliquely along an outer surface of the electrode wire in the insertion portion.

5. The lead of claim 1 , wherein a plurality of first electrodes is arranged in a form of point electrodes on an outer surface of the electrode wire in the insertion portion.

6. A lead system implanted in a body to apply electrical stimulation to body organs, the lead system comprising:
a main processor connected to an external device for communication and control;
one or more leads implanted in a body to apply electrical stimulation to body organs;
an electrode clamp for electrical connection with the lead; and
at least one of a manual operation member configured to be manually operated by an operator or a controller driven according to a control signal from the main processor, the manual operation member and the controller operable to insert, remove, or rotate the lead,
wherein the lead comprises:
an electrode wire having one end provided as an insertion portion to be inserted into a body and the other end provided as an interface portion for connection with an external device;
a plurality of first electrodes in the insertion portion to transmit electrical stimulation to body organs;
a plurality of second electrodes on the interface portion to receive electrical stimulation applied from outside;
a plurality of signal lines that interconnect the first electrodes and the second electrode respectively to transmit electrical stimulation received by the second electrode to the first electrode;
a ring member comprised of an insulating material that prevents exposure of electrical stimulation therethrough, that is disposed on the electrode wire to cover the first electrode, having an opening that exposes the first electrode in a portion of a circumferential direction, and being mounted on the electrode wire to be movable in a longitudinal or circumferential direction with respect to the electrode wire by an external force applied by the manual operation member or the controller to adjust an exposure position of the first electrode through the opening; and
a guide wire inserted into an inner space of the electrode wire to support the electrode wire when the electrode wire is inserted into a brain region,
wherein the ring member is comprised of a plurality of ring members arranged adjacent to each other in a longitudinal direction at the insertion portion of the electrode wire,
wherein each of the plurality of ring members is independently rotatable by the manual operation member or the controller to selectively adjust its position in the circumferential direction and the position of the opening to expose the first electrode through the opening of each of the plurality of ring members and to provide selective areas of the applied electrical stimulation from the first electrode through the openings.

7. The lead system of claim 6 , wherein the controller comprises:
a driving element, including a linear motor and a rotary motor, driven according to a control signal from the main processor; and
an operation key driven in an extension direction and a circumferential direction of the lead by the driving element, one end disposed adjacent to the ring member, and having a magnetic force,
wherein the one end of the operation key is magnetized by application of electric power to apply a magnetic force to at least one of the plurality of ring members to at least one of move or rotate the ring member as the operation key is moved or rotated.

8. The lead system of claim 7 , wherein the operation key is at a position of the guide wire of the lead, and is arranged to be inserted into the position of the guide wire in a state in which the guide wire is removed.

9. The lead system of claim 6 , wherein the manual operation member comprises:
a main body extending in a longitudinal direction of the lead;
a mobile clamp provided on an upper end of the main body and applied with an operating force by an operator; and
a press element that is expanded by the operating force applied to the mobile clamp,
wherein the press element is arranged between openings of the ring member and expanded by the operating force to expand the openings.

10. The lead system of claim 6 , wherein the manual operation member is a case member, coupling the plurality of ring members, configured to surround the lead in a cylindrical shape with both ends open,
wherein a male screw is formed on each of the plurality of ring members, and a female screw is formed at a position in contact with each of the ring members in the case member, so that the case member and the ring members are screwed together.

11. The lead system of claim 10 , wherein, when the case member is rotated in a first direction, the case member is screwed with the plurality of ring members to rotate each of the ring members in the first direction to adjust a position of the ring members in the circumferential direction with respect to the lead, and when the case member is rotated in a second direction opposite to the first direction, the screw coupling between the case member and the plurality of ring members is released to separate the case member.

Assignees

• Samsung Life Public Welfare Foundation

Inventors

• Park Eun Kyoung
• Kim Tae Kyung
• Kang Min Hee
• Lee Kyu Sung

Classifications

• A61N1/36128

  Control systems · CPC title

• A61N1/36125

  Details of circuitry or electric components · CPC title

• A61N1/37514

  Brain implants · CPC title

• A61N1/37518

  Anchoring of the implants, e.g. fixation · CPC title

• A61N1/36096

  Mood disorders, e.g. depression, anxiety or panic disorder · CPC title