Systems and methods for thermal treatment of tissue

Patent metadata

Field	Value
Publication number	US-12383422-B2
Application number	US-201816478839-A
Country	US
Kind code	B2
Filing date	Jan 19, 2018
Priority date	Jan 19, 2017
Publication date	Aug 12, 2025
Grant date	Aug 12, 2025

Abstract

Systems and methods for a medical device configured to provide cooling to a tissue region are provided. The medical device may be configured to noninvasively or invasively cool the tissue region to a predetermined operating temperature via a two-phase heat transfer process.

First claim

We claim:

1. A noninvasive medical device configured to provide cooling to a tissue region, the noninvasive medical device comprising:
a top plate;
a bottom plate including a contact surface;
an evaporative structure arranged between the top plate and the bottom plate configured to receive a working fluid, wherein the evaporative structure is configured to promote evaporation of the working fluid to cool the contact surface; and
an opening extending through the top plate, the bottom plate, and the evaporative structure, wherein the opening enables fractional heat treatment to be performed on the tissue region via the opening.

2. The noninvasive medical device of claim 1 , wherein further comprising a plurality of openings arranged in a fractional pattern of the fractional medical treatment.

3. The noninvasive medical device of claim 1 , wherein the top plate, the bottom plate, and the evaporative structure is included in a base that includes a plurality of array tiles each including a plurality of array units, wherein the plurality of array units each include a proximal end, a distal end, and a portion of a plurality of channels arranged thereon.

4. The noninvasive medical device of claim 1 , wherein the evaporative structure is in the form of a porous substrate.

5. The noninvasive medical device of claim 1 , wherein the evaporative structure is in the form of a metal foam.

6. The noninvasive medical device of claim 1 , wherein the evaporative structure is in the form of a plurality of channels extending from the opening.

7. The noninvasive medical device of claim 1 , wherein the contact surface defines at least one of a concave shape, a convex shape, or a plurality of peaks and valleys.

8. The noninvasive medical device of claim 1 , wherein the contact surface includes a plurality of protrusions extending therefrom.

9. The noninvasive medical device of claim 1 , wherein the bottom plate defines at least one of a horseshoe shape, a banana shape, or an annular shape.

10. The noninvasive medical device of claim 1 , wherein the opening is sealed between the top first plate and the bottom plate.

11. The noninvasive medical device of claim 1 , wherein the working fluid is supplied to the evaporative structure from a fluid source.

12. The noninvasive medical device of claim 1 , wherein the working fluid is at least one of a hydrocarbon, a hydrofluorocarbon, an alcohol, or water.

13. A medical device configured to provide cooling to a tissue region, the medical device comprising:
an evaporative structure including:
a plurality of channels each configured to receive a working fluid; and
a plurality of apertures extending through the evaporative structure, the plurality of apertures to enable fractional heat treatment to be performed on the tissue region via the plurality of apertures; and

a contact surface in engagement with the evaporative structure, wherein the plurality of apertures extend through the contact surface, and
wherein heat from the contact surface is transferred to the evaporative structure to evaporate the working fluid in the plurality of channels and provide cooling to the contact surface adjacent to the plurality of apertures.

14. The medical device of claim 13 , wherein the working fluid is supplied to the plurality of channels from a fluid source.

15. The medical device of claim 13 , wherein the working fluid is at least one of a hydrocarbon, a hydrofluorocarbon, an alcohol, or water.

16. The medical device of claim 13 , wherein the contact surface defines at least one of a concave shape, a convex shape, or a plurality of peaks and valleys.

17. The medical device of claim 13 , wherein the contact surface includes a plurality of protrusions extending therefrom.

18. The medical device of claim 13 , wherein a bottom plate of the medical device defines at least one of a horseshoe shape, a banana shape, or an annular shape.

19. The medical device of claim 13 , wherein the evaporative structure is sealed between a top plate and a bottom plate, and wherein the contact surface is formed on the bottom plate.

20. The medical device of claim 19 , wherein the plurality of apertures extend through the top plate and the bottom plate.

Assignees

• Massachusetts Gen Hospital

Inventors

• Manstein Dieter
• Miralipour Seyed Reza Monazami

Classifications

• A61F2007/126

  for invasive application, e.g. for introducing into blood vessels · CPC title

• A61F2007/0258

  with a fluid permeable layer · CPC title

• A61F2007/0096

  with a thermometer · CPC title

• A61F2007/0068

  evaporating on the spot to be cooled · CPC title

• A61F2007/0058

  evaporating on or near the spot to be cooled · CPC title