Sterilization system and method

Patent metadata

Field	Value
Publication number	US-12377181-B2
Application number	US-202117243328-A
Country	US
Kind code	B2
Filing date	Apr 28, 2021
Priority date	Apr 30, 2020
Publication date	Aug 5, 2025
Grant date	Aug 5, 2025

Abstract

A sterilization system includes a vessel defining a chamber configured to receive one or more materials, a hydrogen peroxide solution positioned within the chamber, and a nonreactive fiber matrix positioned within the chamber, wherein evacuation of the chamber causes vaporization of the hydrogen peroxide in the hydrogen peroxide solution to disinfect the materials positioned in the chamber.

First claim

What is claimed is:

1. A sterilization system comprising:
a vessel defining a chamber, the chamber configured to receive one or more materials;
a hydrogen peroxide solution positioned within the chamber;
a non-reactive fiber matrix positioned within the chamber;
a support assembly positioned within the chamber, the support assembly configured to support the one or more materials; and
a vacuum source in fluid communication with the chamber, the vacuum source configured to evacuate the chamber,
wherein evacuation of the chamber causes vaporization of the hydrogen peroxide in the hydrogen peroxide solution to disinfect the one or more materials positioned in the chamber,
wherein the non-reactive fiber matrix is formed of a material that has high surface area, wicking capability, and low reactivity to hydrogen peroxide,
wherein the non-reactive fiber matrix is positioned within a receptacle formed at a bottom of the chamber, and
wherein the non-reactive fiber matrix is configured to increase the rate of vaporization of the hydrogen peroxide solution.

2. The sterilization system of claim 1 , further comprising a controller and one or more sensors in communication with the controller, the controller configured to control the vacuum source based on feedback from the one or more sensors.

3. The sterilization system of claim 1 , wherein the non-reactive fiber matrix includes a woven fiberglass mat, or a nonwoven fiberglass mat.

4. A sterilization system comprising:
a vessel defining a chamber configured to receive one or more materials;
a purge tank fluidly connected to the vessel via a first conduit
a first valve positioned within the first conduit, wherein the purge tank is configured to capture vapor from the chamber when the first valve is in an open position;
a hydrogen peroxide solution positioned within the chamber;
a non-reactive fiber matrix positioned within the chamber;
a vacuum source fluidly connected to the vessel and the purge tank via a second conduit; and
a second valve positioned within the second conduit, wherein the vacuum source is configured to evacuate the chamber when the first valve is in the open position and the second valve is in an open position;
wherein evacuation of the chamber with the vacuum source causes vaporization of the hydrogen peroxide in the hydrogen peroxide solution to disinfect the one or more materials positioned in the chamber,
wherein the non-reactive fiber matrix is formed of a material that has high surface area, wicking capability, and low reactivity to hydrogen peroxide,
wherein the non-reactive fiber matrix is positioned within a receptacle formed at a bottom of the chamber, and
wherein the non-reactive fiber matrix is configured to increase the rate of vaporization of the hydrogen peroxide solution.

5. The sterilization system of claim 4 , further comprising a controller and one or more sensors in communication with the controller, the controller configured to control the vacuum source based on feedback from the one or more sensors.

6. The sterilization system of claim 5 , wherein the controller is configured to control the first valve and the second valve to control the vacuum source based on feedback from the one or more sensors.

7. The sterilization system of claim 4 , wherein the non-reactive fiber matrix includes a woven fiberglass mat, or a nonwoven fiberglass mat.

8. The sterilization system of claim 4 , wherein the hydrogen peroxide solution is fed into the chamber with a dispenser, the dispenser being configured to automatically dispense hydrogen peroxide solution into the chamber of the vessel.

9. A method of sterilizing one or more materials, the method comprising:
providing a sterilization system of claim 1 ;
positioning the one or more materials within the chamber;
combining the hydrogen peroxide solution with the non-reactive fiber matrix within the vessel; and
vaporizing the hydrogen peroxide in the hydrogen peroxide solution to sterilize the one or more materials within the chamber.

10. The method of claim 9 , wherein the vaporizing the hydrogen peroxide in the hydrogen peroxide solution includes evacuating, with the vacuum source, the chamber.

11. The method of claim 9 , further comprising actuating the vacuum source to achieve a vacuum level that is below a room-temperature vapor pressure of hydrogen peroxide.

12. The method of claim 9 , wherein the combining the hydrogen peroxide solution with the non-reactive fiber matrix includes dispensing the hydrogen peroxide solution into the chamber until some or all of the hydrogen peroxide solution is evaporated.

13. The method of claim 9 , further comprising evaporating the hydrogen peroxide solution under low-pressure conditions.

14. The method of claim 13 , further comprising evaporating the hydrogen peroxide solution until a partial pressure of hydrogen peroxide vapor reaches a first pre-determined level and a partial pressure of water vapor reaches a second pre-determined level.

15. The method of claim 14 , further comprising actuating the vacuum source and evacuating the hydrogen peroxide vapor and water vapor from the chamber.

Assignees

• Wallace David
• Patterson John
• Dave Nikhil
• Chowdhury Abhik
• Pascavis Katie Sue
• Univ Arizona State

Inventors

• Wallace David
• Patterson John
• Dave Nikhil
• Chowdhury Abhik
• Pascavis Katie Sue

Classifications

• A61L2103/15

  Laboratory, medical or dentistry appliances, e.g. catheters or sharps · CPC title

• A61L2202/11

  Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps · CPC title

• A61L2202/14

  Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs · CPC title

• A61L2202/15

  Biocide distribution means, e.g. nozzles, pumps, manifolds, fans, baffles, sprayers · CPC title

• A61L2/26

  Accessories · CPC title