Substituted sulfoximine derivatives

US12377070B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12377070-B2
Application numberUS-202017642184-A
CountryUS
Kind codeB2
Filing dateSep 11, 2020
Priority dateSep 12, 2019
Publication dateAug 5, 2025
Grant dateAug 5, 2025

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  1. Title

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present invention relates to novel heterocyclic compounds of general formula (I) their tautomers, stereoisomers, enantiomers, pharmaceutically acceptable salts and pharmaceutical composition. The compounds of general formula (I) belongs to the family of NOD like receptor family (NLR) protein NLRP3 modulators. The present invention thus relates to novel NLRP3 modulators and use of these novel inhibitor compounds in the treatment of disease or conditions as well as treatment of disease states mediated by NLRP3 as well as treatment of diseases or conditions in which interleukin 1β activity and interleukin-18 (IL-18) is implicated.

First claim

Opening claim text (preview).

We claim: 1. Compound(s) having structure of general formula (I) their tautomeric forms, their stereoisomers, their enantiomers, their pharmaceutically acceptable salts, and pharmaceutical compositions containing them wherein, ‘A’ is selected from optionally substituted groups selected from (C 3 -C 8 )cycloalkyl, (C 6 -C 10 )aryl, heteroaryl, and heterocyclyl groups each…

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What does patent US12377070B2 cover?
The present invention relates to novel heterocyclic compounds of general formula (I) their tautomers, stereoisomers, enantiomers, pharmaceutically acceptable salts and pharmaceutical composition. The compounds of general formula (I) belongs to the family of NOD like receptor family (NLR) protein NLRP3 modulators. The present invention thus relates to novel NLRP3 modulators and use of these nove…
Who is the assignee on this patent?
Cadila Healthcare Ltd, Zydus Lifesciences Ltd
What technology area does this patent fall under?
Primary CPC classification A61K45/06. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).