Composition for improving respiratory diseases using Lactobacillus plantarum strain

Patent metadata

Field	Value
Publication number	US-12376615-B2
Application number	US-202017767181-A
Country	US
Kind code	B2
Filing date	Oct 8, 2020
Priority date	Oct 8, 2019
Publication date	Aug 5, 2025
Grant date	Aug 5, 2025

Abstract

The present invention relates to a food composition for enhancing respiratory function and improving respiratory diseases, using Lactobacillus plantarum KF511 strain; a health functional food comprising the food composition; and a pharmaceutical composition for preventing or treating the respiratory diseases, comprising Lactobacillus plantarum strain, its culture solution, its concentrate, or its dried product, as an active ingredient.

First claim

What are claimed are:

1. A food composition for enhancing respiratory function and improving respiratory diseases, comprising:
Lactobacillus plantarum KF511 strain ( L. plantarum KF511);
a culture solution comprising L. plantarum KF511;
a concentrate comprising L. plantarum KF511; or
a dried product comprising L. plantarum KF511;

wherein the food composition comprises 10 7 to 10 12 CFU of the L. plantarum KF511, the L. plantarum KF511 is an active ingredient in the food composition and is assigned an accession number KCCM 12573P.

2. The food composition according to claim 1 , wherein the respiratory diseases are pulmonary diseases accompanied by symptoms of cough, sputum, dyspnea, airway hypersensitivity, airway obstruction, mucus hypersecretion, decreased expiratory flow rate and/or gas exchange disorder.

3. The food composition according to claim 1 , wherein the respiratory diseases are asthma, chronic obstructive pulmonary disease (COPD), diffuse interstitial pulmonary disease, acute respiratory distress syndrome (ARDS), or acute lung injury.

4. The food composition according to claim 3 , wherein the respiratory diseases are the asthma or the COPD.

5. A health functional food comprising the food composition according to claim 1 .

6. A pharmaceutical composition for preventing or treating respiratory diseases, comprising:
Lactobacillus plantarum KF511 strain ( L. plantarum KF511);
a culture solution comprising L. plantarum KF511;
a concentrate comprising L. plantarum KF511; or
a dried product comprising L. plantarum KF511;

wherein the pharmaceutical composition comprises 10 7 to 10 12 CFU of the L. plantarum KF511, the L. plantarum KF511 is an active ingredient in the pharmaceutical composition and is assigned an accession number KCCM 12573P.

7. The pharmaceutical composition according to claim 6 , wherein the respiratory diseases are asthma, chronic obstructive pulmonary disease (COPD), diffuse interstitial pulmonary disease, acute respiratory distress syndrome (ARDS), or acute lung injury.

8. The pharmaceutical composition according to claim 7 , wherein the respiratory diseases are the asthma or the COPD.

Assignees

• Korea Food Res Inst

Inventors

• Lee So Young
• Kim Seung Yong
• Nam Young Do
• Park So Lim
• Shin Dong Uk
• Shin Hee Soon
• Eom Ji Eun
• Jung Sun Young
• Choi Dae Woon

Classifications

• A61K35/747

  Lactobacilli, e.g. L. acidophilus or L. brevis · CPC title

• C12R2001/25

  Lactobacillus plantarum · CPC title

• A61P11/00

  Drugs for disorders of the respiratory system · CPC title

• A61K36/282

  Artemisia, e.g. wormwood or sagebrush · CPC title

• A61K2236/37

  Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction · CPC title