Bio-based material with antibacterial effect and use thereof

Patent metadata

Field	Value
Publication number	US-12376587-B2
Application number	US-201817053702-A
Country	US
Kind code	B2
Filing date	Jun 15, 2018
Priority date	May 8, 2018
Publication date	Aug 5, 2025
Grant date	Aug 5, 2025

Abstract

Provided is a bio-based material having an antibacterial effect, comprising a polymer represented by a formula (1) or a mixture of the polymer represented by the formula (1) and polyethylene glycol as an antibacterial active ingredient. The use of the bio-based material is also mentioned. The antibacterial bio-based material has excellent, stable and long-lasting antibacterial activity, and has remarkable antibacterial effects against various bacteria and fungi. The antibacterial bio-based material also has excellent biodegradability and biocompatibility, is derived from bio-based products produced by microbial fermentation, has high safety and is suitable for industrial production and large-scale use.

First claim

We claim:

1. A bio-based material with antibacterial and antifungal effect comprising a mixture of
a polymer represented by formula (1) as an antibacterial and antifungal active ingredient,

wherein R represents methyl, m represents 1, n represents an integer of 1-20, and the end groups are hydroxyl and carboxyl groups, respectively; and
polyethylene glycol having a number average molecular weight of 600, and
wherein in the mixture, the mass ratio of the polymer represented by formula (1) to the polyethylene glycol is 1:1.

2. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein the mixture of the polyethylene glycol and the polymer represented by the formula (1) is used as the antibacterial and antifungal active ingredient.

3. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein a preparation process of the mixture comprises mixing the polymer represented by formula (1) and the polyethylene glycol at 80-300° C. and stirring for 10 min-6 h.

4. A method of preparing an antibacterial and antifungal material comprising:
combining the bio-based material of claim 1 with a substrate.

5. A method of preparing an antibacterial and antifungal material comprising:
obtaining a polymer represented by formula (1), and
combining the polymer represented by formula (1) with polyethylene glycol in a mass ratio of the nolvmer represented by formula (1) to the polyethylene glycol of 1:1

wherein R represents methyl, m represents 1, n represents an integer of 1-20, and the end groups are hydroxyl and carboxyl groups, respectively, and
wherein the polyethylene glycol has a number average molecular weight of 600.

6. The method according to claim 4 , wherein the antibacterial and antifungal material is one or more of antibacterial and antifungal formulations, antibacterial and antifungal fabrics, sanitary products and medical materials.

7. The method according to claim 5 , wherein the antibacterial and antifungal material is one or more of antibacterial and antifungal formulations, antibacterial and antifungal fabrics, sanitary products and medical materials.

8. The method according to claim 4 , wherein the substrate is one or more of a textile, food packaging, wound covering materials, dressings, surgical sutures, implant materials, drug carriers, biomedical materials, and tissue engineering scaffolds.

9. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein in the formula (1), n represents an integer of 4-13.

10. The method according to claim 5 , wherein in the formula (1), n represents an integer of 4-13.

11. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein in the formula (1), n represents an integer of 1-6.

12. The method according to claim 5 , wherein in the formula (1), n represents an integer of 1-6.

13. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein the bio-based material consists of the mixture.

14. The bio-based material with antibacterial and antifungal effect according to claim 1 , wherein the bio-based material consists essentially of the mixture.

Assignees

• Hong Kong Res Inst Textiles & Apparel Ltd

Inventors

• Tao Xiaoming
• Yang Xingxing
• Zhang Ziheng
• Li Jun
• Liu Shirui
• Ma Linlin
• Fei Bin
• Leung Hang Mei

Classifications

• C08G63/06 Primary

  derived from hydroxycarboxylic acids · CPC title

• C07C69/675

  of saturated hydroxy-carboxylic acids · CPC title

• A61L2300/404

  Biocides, antimicrobial agents, antiseptic agents · CPC title

• A61L31/16

  Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)} · CPC title

• A61L31/10

  Macromolecular materials · CPC title