Macromolecular compound
US-2016372675-A1 · Dec 22, 2016 · US
Method for preparing 2-iodoheterocyclic aryl ether at room temperature
US12371413B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12371413-B2 |
| Application number | US-202118012586-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 22, 2021 |
| Priority date | Feb 22, 2021 |
| Publication date | Jul 29, 2025 |
| Grant date | Jul 29, 2025 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Disclosed is a method for preparing a 2-iodoheterocyclic aryl ether at room temperature, including adding an alkali metal hydride and a phenol to a solvent, then adding a diiodoheterocyclic aromatic hydrocarbon, and performing a reaction at 0-100° C., so as to obtain a 2-iodoheterocyclic aryl ether product. In the coupling process of the present invention, no transition metal catalyst needs to be added, and no metal pollution will be caused to the product. The product of the present invention can be used as an organic synthesis raw material for a further reaction, and can also be used as an additive flame retardant reagent to improve the flame retardant performance of plastics.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for preparing a 2-iodo-heterocyclic aromatic ether at room temperature comprising following steps: reacting a 2-iodo-heterocyclic aromatic hydrocarbon with a phenol in the presence of an alkali metal hydride to obtain the 2-iodo-heterocyclic aromatic ether, wherein the 2-iodo-heterocyclic aromatic ether is and Ar 2 is benzene, naphthalene, pyridine, quinoline, pyrimidine, or thiophene. 2. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 1 , comprising adding the alkali metal hydride and the phenol into a solvent, then adding the 2-iodo-heterocyclic aromatic hydrocarbon to obtain the 2-iodo-heterocyclic aromatic ether. 3. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 2 , wherein the solvent is one or more selected from the group consisting of DMF, DMA, THF, 2-MeTHF, DME, MTBE, diethyl ether, DMSO, NMP, and toluene. 4. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 1 , wherein the alkali metal hydride is sodium hydride, potassium hydride or calcium hydride; the phenol is unsubstituted phenol, a substituted phenol or a heterocyclic phenol. 5. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 1 , wherein a mole ratio of the phenol to the 2-iodo-heterocyclic aromatic hydrocarbon to the alkali metal hydride is 1:(0.1-10):(1.2-10). 6. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 5 , wherein a mole ratio of the phenol to the 2-iodo-heterocyclic aromatic hydrocarbon to the alkali metal hydride is 1:(0.5-5):(1.5-5). 7. The method for preparing the 2-iodo-heterocyclic aromatic ether at room temperature according to claim 1 , wherein a reaction temperature is 10-50° C.; a reaction time is 0.2-10 hours.
Assignees
Inventors
Classifications
Halogen atoms · CPC title
- C07D333/32Primary
Oxygen atoms · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US12371413B2 cover?
- Disclosed is a method for preparing a 2-iodoheterocyclic aryl ether at room temperature, including adding an alkali metal hydride and a phenol to a solvent, then adding a diiodoheterocyclic aromatic hydrocarbon, and performing a reaction at 0-100° C., so as to obtain a 2-iodoheterocyclic aryl ether product. In the coupling process of the present invention, no transition metal catalyst needs to …
- Who is the assignee on this patent?
- Univ Soochow
- What technology area does this patent fall under?
- Primary CPC classification C07D333/32. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 29 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).