Compounding device, system, kit, software, and method

Patent metadata

Field	Value
Publication number	US-12370355-B2
Application number	US-202218148742-A
Country	US
Kind code	B2
Filing date	Dec 30, 2022
Priority date	Apr 23, 2015
Publication date	Jul 29, 2025
Grant date	Jul 29, 2025

Abstract

An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.

First claim

What is claimed is:

1. A method for using a transfer set with a compounding device, comprising:
providing the transfer set that includes a housing with at least one primary intake port and at least one secondary intake port, a first flexible output line extending from the housing, and a second flexible output line extending from the housing;
providing the compounding device that includes a housing, a first pump, and a second pump;
connecting the housing of the transfer set to the housing of the compounding device;
leading the first flexible output line onto the first pump to attach the first flexible output line to the first pump; and
leading the second flexible output line onto the second pump to attach the second flexible output line to the second pump.

2. The method of claim 1 , further comprising:
providing at least one first flexible input line, and a plurality of second flexible input lines on the housing;
connecting the first flexible input line to a first source container; and
connecting at least one of the second flexible input lines to a second source container.

3. The method of claim 2 , wherein a cross-sectional diameter taken normal to a flow path of the first flexible input line is different in size as compared to a cross-sectional diameter taken normal to a flow path of the at least one of the second flexible input lines.

4. The method of claim 1 , further comprising:
causing a first fluid to flow through the housing of the transfer set along a first channel; and
causing a second fluid and third fluid different from the second fluid to flow through the housing of the transfer set along a second channel that is different from and separated from the first channel such that the first fluid does not mix with the second fluid and third fluid while in the housing, and such that the second fluid and third fluid mix within the housing.

5. The method of claim 1 , further comprising:
providing the housing with at least one primary valve that includes a wall;
causing fluid to turn greater than 90 degrees along a fluid pathway after entering a valve inlet of the at least one primary valve and prior to exiting a side outlet of the at least one primary valve.

6. The method of claim 1 , further comprising:
placing the housing of the transfer set onto the compounding device to engage at least one attachment structure of the transfer set with a mating attachment structure on the compounding device.

7. The method of claim 1 , further comprising:
providing at least one primary valve in the compounding device including a primary valve mating structure;
mating the primary valve mating structure with a primary actuator member located on the compounding device when attaching the transfer set housing to the compounding device.

8. The method of claim 1 , further comprising:
confirming through the use of a sensor that the housing is in a correct and operational position with respect to the compounding device.

9. The method of claim 1 , further comprising:
providing a strain relief connected to both of the at least one primary flexible output line and the at least one secondary flexible output line.

10. The method of claim 1 , further comprising:
providing a union junction connected to both the at least one primary flexible output line and the at least one secondary flexible output line;
mixing fluid from a fluid path defined by the at least one primary flexible output line with fluid from a fluid path defined by the at least one secondary flexible output line at the union junction.

11. The method of claim 1 , further comprising:
providing a branch junction connected to the at least one secondary flexible input line;
providing a flex line connected to the branch junction and in fluid communication with the first channel
causing a first portion of fluid located in the at least one secondary flexible input line upstream of the branch junction to enter the first channel; and
causing a second portion of fluid located in the at least one secondary flexible input line upstream of the branch junction to enter the second channel.

12. A method for using a transfer set with a compounding device, comprising:
providing the transfer set that includes a housing having a top surface, a bottom surface, and a side surface extending from the top surface to the bottom surface, the bottom surface configured for attachment to the compounding device, the top surface of the housing including at least one primary intake port and at least one secondary intake port, the side surface of the housing including a first flexible output line and a second flexible output line extending from the side surface of the housing;
connecting the bottom surface of the housing to the compounding device;
extending the first flexible output line in a direction substantially orthogonal to a direction normal to the top surface of the housing of the transfer set to a first pump; and
extending the second flexible output line in a direction substantially orthogonal to the direction normal to the top surface of the housing of the transfer set to a second pump.

13. The method of claim 12 , further comprising:
causing a first fluid to flow through the housing of the transfer set along a first channel; and
causing a second fluid and third fluid different from the second fluid to flow through the housing of the transfer set along a second channel that is different from and separated from the first channel such that the first fluid does not mix with the second fluid and third fluid while in the housing, and such that the second fluid and third fluid mix within the housing.

14. The method of claim 12 , further comprising:
providing the housing with at least one primary valve that includes a wall;
causing fluid to turn greater than 90 degrees along a fluid pathway after entering a valve inlet of the at least one primary valve and prior to exiting a side outlet of the at least one primary valve.

15. The method of claim 12 , further comprising:
pushing the housing of the transfer set down onto the compounding device to engage at least one attachment structure of the transfer set with a mating attachment structure on the compounding device.

16. The method of claim 12 , further comprising:
providing at least one first flexible input line connected to the at least one primary intake port, and a second flexible input line connected to the at least one secondary intake port;
connecting the first flexible input line to a first source container; and
connecting the second flexible input line to a second source container different from the first source container.

17. The method of claim 16 , wherein a cross-sectional diameter taken normal to a flow path of the first flexible input line is different in size as compared to a cross-sectional diameter taken normal to a flow path of the at least one of the second flexible input line.

18. A method for using a transfer set with a compounding device, comprising:
providing the transfer set that includes a housing with at least one primary intake port and at least one secondary intake port, a first flexible output line extending from the housing, and a second flexible output line extending from the housing;
providing the compounding device including a housing with a top surface;
connecting the housing of the transfer set to the top surface of the housing of the compounding device;
leading the first flexible output line onto a first pump located on the top surface of the housing of the compounding device; and
leading the second flexib

Assignees

• Braun Medical Inc

Inventors

• Konrad Jr Karl
• Bartholomew Joel
• Janders Mike
• Ammermann Linda M
• Lane Benjamin R
• Mumpower Mariano
• Pearl Aaron S

Classifications

• F16K2099/0084

  Chemistry or biology, e.g. "lab-on-a-chip" technology · CPC title

• F16K99/0042

  Electric operating means therefor · CPC title

• F16K99/0013

  Rotary valves · CPC title

• F16K31/041

  for rotating valves (F16K31/055 takes precedence) · CPC title

• A61M39/24

  Check- or non-return valves · CPC title