Systems and methods for oxygenator performance evaluation

Patent metadata

Field	Value
Publication number	US-12370294-B2
Application number	US-202117173729-A
Country	US
Kind code	B2
Filing date	Feb 11, 2021
Priority date	Nov 8, 2016
Publication date	Jul 29, 2025
Grant date	Jul 29, 2025

Abstract

Systems and methods for monitoring oxygenator performance in extracorporeal circuit systems or the like. More particularly, the disclosure relates to systems and methods including a controller programmed to determine oxygenator apparatus flow impedance as a function of an inlet pressure measurement, an outlet pressure measurement and a blood flow rate measurement. The systems and methods may include a communication device that receives signals from the controller to communicate information regarding oxygenator apparatus performance.

First claim

What is claimed is:

1. A method for maintaining oxygenating performance of an extracorporeal circuit including an oxygenator apparatus, the method comprising:
determining, via an electronic controller, a first oxygenator apparatus flow impedance at a first point in time;
determining, via the electronic controller, a second oxygenator apparatus flow impedance at a second point in time, the second point in time being after the first point in time;
comparing, via the electronic controller, the first oxygenator apparatus flow impedance to the second oxygenator apparatus flow impedance;
generating, via the electronic controller, oxygenator apparatus flow impedance trending information based on a multiplicity of sequentially determined oxygenator apparatus flow impedances;
determining, via the electronic controller, an end-of-life criteria for the oxygenator apparatus based upon the oxygenator apparatus flow impedance trending information; and
delivering, to the oxygenator apparatus, an anticoagulant dosage revised based on the end-of-life criteria.

2. The method of claim 1 , further comprising providing a communication to a clinician indicative of the oxygenator apparatus flow impedance.

3. The method of claim 2 , wherein the communication is a visual communication.

4. The method of claim 2 , wherein the communication is an audio communication.

5. The method of claim 2 , wherein the communication is provided by a communication device that is carried by a housing of the oxygenator apparatus.

6. The method of claim 1 , wherein the oxygenator apparatus flow impedance is determined as:
(inlet pressure measurement−outlet pressure measurement)/blood flow rate measurement.

7. The method of claim 1 , wherein the oxygenator apparatus includes a housing and a fiber bundle having a plurality of gas exchange elements, the housing defining a blood flow path between a blood inlet port and a blood outlet port, the fiber bundle disposed within the housing.

8. A method for maintaining oxygenating performance of an extracorporeal circuit including an oxygenator apparatus, the method comprising:
determining, via an electronic controller, a baseline oxygenator apparatus flow impedance at a first point in time;
determining, via the electronic controller, a current oxygenator apparatus flow impedance at a second point in time, the second point in time being after the first point in time;
comparing, via the electronic controller, the baseline oxygenator apparatus flow impedance to the current oxygenator apparatus flow impedance;
prompting, via the electronic controller, a communication device to communicate information indicative of the determined oxygenator apparatus flow impedance including prompting the communication device to communicate information indicative of a comparison between the baseline oxygenator apparatus flow impedance and the current oxygenator apparatus flow impedance; and
delivering, to the oxygenator apparatus, an anticoagulant dosage revised based on the comparison between the baseline oxygenator apparatus flow impedance and the current oxygenator apparatus flow impedance.

9. The method of claim 8 , wherein the communication device communicates a visual communication.

10. The method of claim 8 , wherein the communication device communicates an audio communication.

11. The method of claim 8 , wherein the communication device is carried by a housing of the oxygenator apparatus.

12. The method of claim 8 , wherein the oxygenator apparatus flow impedance is determined as:
(inlet pressure measurement−outlet pressure measurement)/blood flow rate measurement.

13. The method of claim 8 , wherein the oxygenator apparatus includes a housing and a fiber bundle having a plurality of gas exchange elements, the housing defining a blood flow path between a blood inlet port and a blood outlet port, the fiber bundle disposed within the housing.

14. A method for maintaining oxygenating performance of an extracorporeal circuit including an oxygenator apparatus, the method comprising:
determining, via an electronic controller, a first oxygenator apparatus flow impedance at a first point in time;
determining, via the electronic controller, a second oxygenator apparatus flow impedance at a second point in time, the second point in time being after the first point in time;
comparing, via the electronic controller, the first oxygenator apparatus flow impedance to the second oxygenator apparatus flow impedance;
generating, via the electronic controller, oxygenator apparatus flow impedance trending information based on multiple, sequential comparisons of the first oxygenator apparatus flow impedance to the second oxygenator apparatus flow impedance;
determining, via the electronic controller, an end-of-life criteria for the oxygenator apparatus based upon the oxygenator apparatus flow impedance trending information; and
delivering, to the oxygenator apparatus, an anticoagulant dosage revised based on the end-of-life criteria.

15. The method of claim 1 , wherein determining the first oxygenator apparatus flow impedance includes:
receiving, via the electronic controller, an inlet pressure measurement at the first point in time from a first sensor proximate a blood inlet port of the oxygenator apparatus;
receiving, via the electronic controller, an outlet pressure measurement at the first point in time from a second sensor proximate a blood outlet port of the oxygenator apparatus;
receiving, via the electronic controller, a blood flow rate measurement at the first point in time from a third sensor of the oxygenator apparatus; and
determining, via the electronic controller, the first oxygenator apparatus flow impedance based on the inlet pressure measurement, the outlet pressure measurement, and the blood flow rate measurement.

16. The method of claim 15 , wherein determining the second oxygenator apparatus flow impedance includes:
receiving, via the electronic controller, an inlet pressure measurement at the second point in time from the first sensor;
receiving, via the electronic controller, an outlet pressure measurement at the second point in time from the second sensor;
receiving, via the electronic controller, a blood flow rate measurement at the second point in time from the third sensor; and
determining, via the electronic controller, the second oxygenator apparatus flow impedance based on the inlet pressure measurement, the outlet pressure measurement, and the blood flow rate measurement.

17. The method of claim 8 , wherein determining the baseline oxygenator apparatus flow impedance includes:
receiving, via the electronic controller, an inlet pressure measurement at the first point in time from a first sensor proximate a blood inlet port of the oxygenator apparatus;
receiving, via the electronic controller, an outlet pressure measurement at the first point in time from a second sensor proximate a blood outlet port of the oxygenator apparatus;
receiving, via the electronic controller, a blood flow rate measurement at the first point in time from a third sensor of the oxygenator apparatus; and
determining, via the electronic controller, the baseline oxygenator apparatus flow impedance based on the inlet pressure measurement, the outlet pressure measurement, and the blood flow rate measurement.

18. The method of claim 17 , wherein determining the current oxygenator apparatus flow impedance includes:
receiving, via the electronic controller, an inlet pressure measurement at the second point in time from the first sensor;
receiving, via th

Assignees

• Medtronic Vascular Inc

Inventors

• Steffens Brian
• Beavers James
• Knoll John
• Romine Todd

Classifications

• A61M2205/70

  with testing or calibration facilities · CPC title

• A61M2205/584

  having a color code · CPC title

• A61M2205/583

  by visual feedback · CPC title

• A61M2205/581

  by audible feedback · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title