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Composition for treating atopy or pruritus comprising N-acetyl or N-acyl amino acid
US12370161B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12370161-B2 |
| Application number | US-202217668678-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 10, 2022 |
| Priority date | Nov 24, 2017 |
| Publication date | Jul 29, 2025 |
| Grant date | Jul 29, 2025 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for decreasing expression of IL-4 and interferon γ in skin tissue in treatment of atopic dermatitis, comprising the steps of: a) identifying a subject having atopic dermatitis; and b) administering a composition to the subject, wherein said composition comprises N-acetyltryptophan or a pharmaceutically acceptable salt thereof as an active ingredient. 2. The method according to claim 1 , wherein the N-acetyltryptophan is N-acetyl-L-tryptophan. 3. The method according to claim 1 , wherein the composition is prepared into a formulation selected from the group consisting of a formulation for external application to skin, an aerosol, a spray, a collyrium, an oral medication, and an injection. 4. The method according to claim 1 , wherein the N-acetyltryptophan consists of N-acetyl-L-tryptophan. 5. The method according to claim 1 , wherein the composition further comprises a surfactant, a sterilizer, an antioxidant, a UV absorber, an anti-inflammatory agent or a cooling agent.
Assignees
Inventors
Classifications
Preparations for dry skin · CPC title
Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin · CPC title
having five membered rings, e.g. pyrrolidone carboxylic acid · CPC title
substituted by amido group(s) · CPC title
Face masks · CPC title
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- What does patent US12370161B2 cover?
- The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problemati…
- Who is the assignee on this patent?
- Stemdr Inc, Nat Univ Chonbuk Ind Coop Found, Korea Res Inst Chemical Tech
- What technology area does this patent fall under?
- Primary CPC classification A61K31/198. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jul 29 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).