Wound dressing for treatment of damaged skin

Patent metadata

Field	Value
Publication number	US-12364784-B2
Application number	US-201917050106-A
Country	US
Kind code	B2
Filing date	May 6, 2019
Priority date	May 8, 2018
Publication date	Jul 22, 2025
Grant date	Jul 22, 2025

Abstract

Adhesive wound dressing that comprises an absorbent matrix (A) adhering to the central portion of a polyurethane backing (B) having an adhesive layer for the skin, said matrix (A) comprising: a. a breathable and porous polyethylene film at the end designed to come into contact with the wound; b. an absorbent layer made of non-woven fabric adjacent to film a), said absorbent layer consisting of: i. 60-65% viscose ii. 25-30% polyester iii. 5-15% polypropylene; c. a layer of polyethylene inserted between layer b) and a layer d. of hydrophobic polystyrene, the latter being in contact with the central portion of polyurethane backing (B); wherein matrix (A) is impregnated with a solution of one or more polysaccharides or the salts thereof.

First claim

The invention claimed is:

1. Adhesive wound dressing which comprises an absorbent matrix (A) adhering to a central portion of a polyurethane backing (B) having an adhesive layer for the skin, said matrix (A) comprising:
a. a breathable and porous polyethylene film at the surface thereof designed to come into contact with the wound;
b. an absorbent non-woven fabric layer adjacent to film a), said absorbent layer consisting of:
i. 60-65% viscose
ii. 25-30% polyester
iii. 5-15% polypropylene;

c. a polyethylene layer inserted between layer b) and a layer
d. of hydrophobic polystyrene, the latter being in contact with the central portion of polyurethane backing (B);
wherein matrix (A) is impregnated with a solution of hyaluronic acid sodium salt with an average molecular weight ranging from 150,000 to 250,000 Da in a concentration from 0.1% to 1% w/w.

2. Wound dressing according to claim 1 wherein the adhesive layer of backing (B) is a layer of polyacrylic glue.

3. Wound dressing according to claim 1 wherein absorbent layer b) consists of:
i. 60% viscose;
ii. 25% polyester;
iii. 15% polypropylene.

4. Wound dressing according to claim 1 wherein the hyaluronic acid sodium salt is present in a concentration of 0.3% w/w.

5. Wound dressing according to claim 1 wherein matrix (A) has an average thickness ranging from 2.5 (±0.3) to 3.0 (±0.3) mm.

6. Wound dressing according to claim 5 wherein matrix (A) is impregnated to 50% of its maximum absorption capacity by homogeneous spraying of 65±5 mg/cm 2 of the solution containing hyaluronic acid sodium salt.

7. Wound dressing according to claim 6 wherein matrix (A) has an average thickness of 2.7±0.3 mm and an absorption power ≥20 g/100 cm 2 in a time ≤1 sec.

8. Wound dressing according to claim 1 wherein absorbent layer b) consists of 60% viscose, 25% polyester and 15% polypropylene, matrix (A) has an average thickness of 2.7±0.3 mm and an absorbent power ≥20 g/100 cm 2 in a time of ≤1 sec, and is impregnated to 50% of its maximum absorption capacity by homogeneous spraying of 65±5 mg/cm 2 of a solution of hyaluronic acid sodium salt with an average molecular weight ranging between 150,000 and 250,000 Da at the concentration of 0.3% w/w.

9. Wound dressing according to claim 1 wherein matrix (A) contains pharmacologically/biologically active substances selected from iodine, silver sulfadiazine, metallic, colloidal or micronised silver, antibiotics for topical use, local anaesthetics, NSAIDs, steroids for topical use, cytostatics, growth factors, fibrinolytics and antioedema agents, proteolytic enzymes, collagenase, hyaluronidase, anticoagulants, proteins or silk proteins, and Triticum vulgare extract.

10. Wound dressing according to claim 1 for surgical use in the treatment of wounds, burns, ulcers of various kinds, abrasions, and slight or moderate grazes.

11. Wound dressing according to claim 1 for dermatological use in the treatment of local inflammations that may cause skin lesions or microlesions.

12. Wound dressing according to claim 1 for dermocosmetic use in the treatment of skin relaxation with or without lesions or microlesions.

13. Wound dressing according to claim 2 wherein absorbent layer b) consists of:
i. 60% viscose;
ii. 25% polyester;
iii. 15% polypropylene.

14. Wound dressing according to claim 1 wherein matrix (A) contains pharmacologically/biologically active substances selected from collagen and fibroin.

Assignees

• Fidia Farm Spa

Inventors

• Campisi Monica
• Gennari Giovanni

Classifications

• A61L2300/42

  Anti-thrombotic agents, anticoagulants, anti-platelet agents · CPC title

• A61L2300/41

  Anti-inflammatory agents, e.g. NSAIDs · CPC title

• A61L2300/406

  Antibiotics · CPC title

• A61L2300/402

  Anaestetics, analgesics, e.g. lidocaine · CPC title

• A61L2300/30

  Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera · CPC title