Automatic analysis device and automatic analysis method of specimen

Patent metadata

Field	Value
Publication number	US-12360077-B2
Application number	US-202017627240-A
Country	US
Kind code	B2
Filing date	Mar 11, 2020
Priority date	Jul 22, 2019
Publication date	Jul 15, 2025
Grant date	Jul 15, 2025

Abstract

An automatic analysis device 100 includes an electrolyte measurement unit 114 that executes internal standard solution measurement once or more at least before potential measurement of the specimen, and when the potential measurement of the specimen is continuously executed by the electrolyte measurement unit 114 , a measurement operation of the internal standard solution before the potential measurement is changed depending on whether there is a possibility that the specimen measured immediately before is a high concentration specimen. This provides an automatic analysis device and an automatic analysis method of a specimen that are capable of improving the processing capacity of the entire device by reducing the carry-over and ensuring measurement accuracy in performing electrolyte measurement.

First claim

The invention claimed is:

1. An automatic analysis device that automatically analyzes a specimen, the device comprising:
an electrolyte measurement unit configured to execute a measurement operation, in a predetermined cycle, of measuring an internal standard solution once or more at least before a potential measurement of a second specimen,
wherein the potential measurement of the second specimen is continuously executed by the electrolyte measurement unit, and upon determining there is a possibility that a first specimen measured immediately before the second specimen is a high concentration specimen based on a comparison of a first ion concentration measurement range of the first specimen and a second ion concentration measurement range of the second specimen, the measurement operation of the internal standard solution before the potential measurement of the second specimen is changed without changing a duration of the predetermined cycle.

2. The automatic analysis device according to claim 1 , further comprising:
a controller coupled to the electrolyte measurement unit, the controller being configured to store information for each of a plurality of specimen types, the first specimen and the second specimen being different specimen types,
wherein the information includes the first ion concentration measurement range and the second ion measurement range.

3. The automatic analysis device according to claim 1 , further comprising:
a controller coupled to the electrolyte measurement unit, the controller being configured to, upon determining there is the possibility that the first specimen is the high concentration specimen, control the electrolyte measurement unit to suck at least one of the internal standard solution and a diluent for diluting the second specimen to an electrode of the electrolyte measurement unit.

4. The automatic analysis device according to claim 1 , further comprising:
a storage medium, the storage medium storing a first time chart defining a timing of the operation of the electrolyte measurement unit that is used upon determining there is no possibility that the first specimen is a high concentration specimen, and a second time chart defining the operation of the electrolyte measurement unit that is used upon determining there is a possibility that the second specimen is a high concentration specimen.

5. The automatic analysis device according to claim 4 ,
wherein the first time chart includes an idle time at which the electrolyte measurement unit does not operate at the beginning of the time chart, and
wherein the second time chart is defined such that during a time corresponding to the idle time of the first time chart, an operation of discharging and sucking at least one of the internal standard solution and a diluent for diluting the specimen is performed.

6. The automatic analysis device according to claim 5 ,
wherein the second time chart is defined such that, among the operation of discharging and sucking at least one of the internal standard solution and the diluent for diluting the specimen, discharging and sucking only the diluent is performed.

7. The automatic analysis device according to claim 5 ,
wherein the second time chart is defined such that, among the operation of discharging and sucking at least one of the internal standard solution and the diluent for diluting the specimen, discharging and sucking both the internal standard solution and the diluent is performed.

8. The automatic analysis device according to claim 7 ,
wherein a user sets discharge amounts of the internal standard solution and the diluent in the second time chart.

9. A method of automatic analysis of a specimen using an automatic analysis device that includes an electrolyte measurement unit, the method comprising:
executing, by the electrolyte measurement unit, a measurement operation, in a predetermined cycle, of measuring an internal standard solution measurement once or more at least before a potential measurement of a second specimen, and
wherein the potential measurement of the second specimen is continuously executed by the electrolyte measurement unit, and upon determining there is a possibility that a first specimen measured immediately before the second specimen is a high concentration specimen based on a comparison of a first ion concentration measurement range of the first specimen and a second ion concentration measurement range of the second specimen, the measurement operation of the internal standard solution before the potential measurement of the second specimen is changed without changing a duration of the predetermined cycle.

Assignees

• Hitachi High Tech Corp

Inventors

• Fukaya Masashi
• Yasui Akihiro

Classifications

• G01N27/38

  Cleaning of electrodes · CPC title

• G01N27/301

  Reference electrodes · CPC title

• G01N2035/0094

  optimisation; experiment design · CPC title

• G01N27/416 Primary

  Systems (G01N27/27 takes precedence) · CPC title

• G01N35/0092 Primary

  Scheduling · CPC title