Volatile applications against pathogens
US-2016374344-A9 · Dec 29, 2016 · US
Series of compounds for treatment of skin diseases and other conditions
US12358859B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12358859-B2 |
| Application number | US-202217887480-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 14, 2022 |
| Priority date | Oct 14, 2018 |
| Publication date | Jul 15, 2025 |
| Grant date | Jul 15, 2025 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
Compounds and methods related to the prevention and treatment of diseases and conditions, some of which are facilitated by melanogenesis are disclosed. Specifically, the present subject matter includes a series of compounds and compositions and their use for anti-melanogenic and antioxidant activity. This subject matter also includes the treatment of skin disorder due to acne vulgaris and related inflammatory and post inflammatory hyperpigmentation. Methods for synthesizing contemplated compounds are also disclosed.
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound selected from the group consisting of (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14). 2. A composition comprising (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 3. A method for inhibiting the production of melanin comprising administering to a subject in need thereof a composition comprising at least one of the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 4. A method for preventing and treating diseases and conditions related to the overproduction or uneven distribution of melanin comprising administering to a subject in need thereof an effective amount of a composition comprising at least one of the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 5. A method for whitening and/or lightening skin comprising administering to a subject in need thereof a composition comprising at least one of the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 6. A method for inhibit the browning and color changes in fruits, vegetables, juices and other food products comprising administering a composition comprising at least one of the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 7. A method for suppressing the activity of Propionibacterium ( P - acnes ) comprising administering to a patient in need thereof a composition comprising at least one the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof. 8. A method for deactivating the activity of proinflammatory cytokines comprising administering to a patient in need thereof a composition comprising at least one of the following compounds: (E)-3-(3,7-dimethylocta-1,6-dienyl) pyridine (12); (E)-2-(3,7-dimethylocta-1,6-dienyl) pyridine (13), (E)-5-(3,7-dimethylocta-1,6-dienyl)-2-methoxypyridine (14) or a pharmaceutically acceptable salt thereof.
Assignees
Inventors
Classifications
with singly-bound oxygen · CPC title
Oxygen atoms · CPC title
containing only one pyridine ring · CPC title
with carbon atoms of the carboxamide groups bound to acyclic carbon atoms · CPC title
containing six-membered aromatic rings and other rings · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US12358859B2 cover?
- Compounds and methods related to the prevention and treatment of diseases and conditions, some of which are facilitated by melanogenesis are disclosed. Specifically, the present subject matter includes a series of compounds and compositions and their use for anti-melanogenic and antioxidant activity. This subject matter also includes the treatment of skin disorder due to acne vulgaris and relat…
- Who is the assignee on this patent?
- Unigen Inc
- What technology area does this patent fall under?
- Primary CPC classification A23B7/154. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jul 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).