Chemical analysis apparatus

Patent metadata

Field	Value
Publication number	US-12350666-B2
Application number	US-202017778326-A
Country	US
Kind code	B2
Filing date	Nov 5, 2020
Priority date	Dec 3, 2019
Publication date	Jul 8, 2025
Grant date	Jul 8, 2025

Abstract

The present invention provides a chemical analyzer with highly reliable agitation performance, said chemical analyzer not only diagnosing the deterioration of a piezoelectric element, but also diagnosing the deformation and displacement of a reaction container and diagnosing the normality of the liquid quantity of a substance to be agitated in the reaction container. This chemical analyzer is characterized by comprising: an agitating mechanism that uses acoustic waves to agitate a sample and a reagent within a reaction container, generates acoustic waves using a piezoelectric element, and has an acoustic wave sensor for detecting the acoustic waves; and a controller that controls the agitating mechanism. Said chemical analyzer is further characterized in that the controller has: an acoustic wave detection unit that processes a detection signal detected by the acoustic wave sensor; a normality information memory in which normal-time information is stored; a signal intensity determination unit that compares the acoustic wave amplitude and acoustic wave frequency transmitted from the acoustic wave detection unit with the acoustic wave amplitude and acoustic wave frequency stored in the normality information memory; and a repeat period determination unit that compares the acoustic wave period characteristic transmitted from the acoustic wave detection unit with the acoustic wave period characteristic stored in the normality information memory.

First claim

The invention claimed is:

1. A chemical analysis apparatus, comprising:
a stirring mechanism that stirs a sample and a reagent using an acoustic wave in a reaction vessel, generates the acoustic wave by a piezoelectric element, and includes an acoustic wave sensor that detects the acoustic wave; and
a controller that controls the stirring mechanism,
wherein the controller includes:
an acoustic wave detection unit that processes a detection signal detected by the acoustic wave sensor;
a normal information memory that stores normal time information;
a signal strength determination unit that compares an amplitude of an acoustic wave and a frequency of an acoustic wave transmitted from the acoustic wave detection unit with an amplitude of an acoustic wave and a frequency of an acoustic wave stored in the normal information memory; and
a repetition cycle determination unit that compares a cycle characteristic of an acoustic wave transmitted from the acoustic wave detection unit with a cycle characteristic of an acoustic wave stored in the normal information memory.

2. The chemical analysis apparatus according to claim 1 , further comprising a deterioration determination unit that determines deterioration of the piezoelectric element and normality of the reaction vessel based on a comparison result in the signal strength determination unit and a comparison result in the repetition cycle determination unit.

3. The chemical analysis apparatus according to claim 2 , wherein a cycle characteristic of the acoustic wave is a cycle of the acoustic wave.

4. The chemical analysis apparatus according to claim 2 , wherein a cycle characteristic of the acoustic wave is a transmission cycle and a reception cycle.

5. The chemical analysis apparatus according to claim 2 , wherein a cycle characteristic of the acoustic wave is propagation time of a reception waveform.

6. The chemical analysis apparatus according to claim 2 , wherein a cycle characteristic of the acoustic wave is a ratio between an amplitude detection time and an amplitude non-detection time.

Assignees

• Hitachi High Tech Corp

Inventors

• Kourai Yuusuke
• Inabe Toshiyuki
• Miyamoto Shunsuke

Classifications

• G01N35/025

  having a carousel or turntable for reaction cells or cuvettes · CPC title

• G01N1/38

  Diluting, dispersing or mixing samples · CPC title

• B01L2400/0439

  ultrasonic vibrations, vibrating piezo elements · CPC title

• B01L2300/0663

  Whole sensors · CPC title

• B01F31/89

  Methodical aspects; Controlling · CPC title