Electrode leads having nerve cuffs and associated systems and methods

Patent metadata

Field	Value
Publication number	US-12350489-B2
Application number	US-202217683598-A
Country	US
Kind code	B2
Filing date	Mar 1, 2022
Priority date	Mar 30, 2021
Publication date	Jul 8, 2025
Grant date	Jul 8, 2025

Abstract

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

First claim

We claim:

1. An electrode lead, comprising:
an elongate lead body having a proximal end and a distal end; and
a nerve cuff including;
a biologically compatible, elastic, electrically insulative cuff body affixed to the distal end of the lead body, the cuff body being configured to be circumferentially disposed around a nerve, having a pre-set furled state that defines an inner lumen, being movable to an unfurled state, including front and rear layers, and defining a length, a length direction, a width in the unfurled state that is greater than the length, and a width direction,
first and second relatively wide electrically conductive members located between the front and rear layers of the cuff body, spaced from one another in the length direction, and extending in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape,
the cuff body front layer including a plurality of openings that are spaced from one another in the width direction and are aligned with, and located inwardly of the perimeter of, the first relatively wide electrically conductive member and a plurality of openings that are spaced from one another in the width direction and are aligned with, and located inwardly of the perimeter of, the second relatively wide electrically conductive member,
a plurality of relatively narrow electrically conductive members located between the front and rear layers of the cuff body, spaced from one another in the width direction, and located between the first and second relatively wide electrically conductive members,
the cuff body front layer including a plurality of openings that are spaced from one another in the width direction and are respectively aligned with the relatively narrow electrically conductive members, and
a plurality of electrical conductors extending through the lead body from at least some of the electrically conductive members to the proximal end of the lead body.

2. The electrode lead as claimed in claim 1 , further comprising:
a plurality of lead connector terminals at the proximal end of the lead body that are connected to the plurality of electrical conductors.

3. The electrode lead as claimed in claim 1 , wherein
the first and second relatively wide electrically conductive members are the same length.

4. The electrode lead as claimed in claim 1 , wherein
the first and second relatively wide electrically conductive members are parallel to one another.

5. The electrode lead as claimed in claim 1 , wherein
all of the relatively narrow electrically conductive members are equidistant from the first and second relatively wide electrically conductive members.

6. The electrode lead as claimed in claim 1 , wherein
the relatively narrow electrically conductive members define respective perimeters; and
the plurality of openings that are respectively aligned with the relatively narrow electrically conductive members are located inwardly of the perimeters.

Assignees

• The Alfred E Mann Foundation For Scient Research

Inventors

• Jenney Christopher Reed
• Gotlib Oren
• Calderon Joseph
• Brandt William Andrew
• Talbot Neil

Classifications

• H01R2201/12

  for medicine and surgery · CPC title

• H01R13/5224

  for medical use · CPC title

• A61N2001/0578

  having means for removal or extraction · CPC title

• A61N1/3752

  Details of casing-lead connections · CPC title

• A61N1/375

  Constructional arrangements, e.g. casings · CPC title