Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter
US-11096712-B2 · Aug 24, 2021 · US
US12350417B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12350417-B2 |
| Application number | US-202016748376-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 21, 2020 |
| Priority date | Jan 21, 2020 |
| Publication date | Jul 8, 2025 |
| Grant date | Jul 8, 2025 |
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In some examples, a medical aspiration system is configured to control medical aspiration based on a cardiac cycle of a patient. For example, a medical aspiration system can include a suction source configured to apply a suction force to a catheter to remove fluid from the catheter, and control circuitry configured to control the suction force applied by the suction source to the catheter based on a cardiac cycle of a patient.
Opening claim text (preview).
What is claimed is: 1. A medical aspiration system comprising: a suction source configured to apply a suction force to a catheter to remove a thrombus from vasculature of a patient using the catheter; and control circuitry configured to control the suction force applied by the suction source to the catheter based on a cardiac cycle of the patient to vary the suction force present at a distal opening of the catheter to facilitate aspiration of the thrombus from the vasculature. 2. The medical aspiration system of claim 1 , wherein the control circuitry is configured to control the suction force applied by the suction source based on the cardiac cycle by at least controlling the suction source to apply a first suction force during diastole and controlling the suction source to apply a second suction force during systole, the first suction force being different from the second suction force. 3. The medical aspiration system of claim 1 , further comprising sensing circuitry configured to generate a signal indicative of the cardiac cycle of the patient, wherein the control circuitry is configured to receive the signal from the sensing circuitry and control the suction force applied to the catheter based on the signal. 4. The medical aspiration system of claim 3 , wherein the signal comprises at least one of an electrocardiogram, an electrogram, a photoplethysmogram, or a blood pressure signal. 5. The medical aspiration system of claim 1 , further comprising the catheter fluidically coupled to the suction source, wherein the catheter comprises a flexible catheter body configured to be navigated through the vasculature of the patient. 6. The medical aspiration system of claim 1 , wherein the control circuitry is configured to control the suction force applied by the suction source to the catheter based on the cardiac cycle by at least cycling the suction source between an on-phase and an off-phase. 7. The medical aspiration system of claim 1 , wherein the control circuitry is configured to synchronize the application of suction force with the cardiac cycle. 8. The medical aspiration system of claim 1 , wherein the control circuitry is configured to synchronize the application of suction force with one portion of the cardiac cycle, and the application of reduced suction force or no suction force with another portion of the cardiac cycle. 9. The medical aspiration system of claim 1 , wherein the control circuitry is configured to synchronize the application of suction force with one portion of the cardiac cycle, and apply reduced suction force or no suction force during the remainder of the cardiac cycle. 10. The medical aspiration system of claim 1 , wherein the suction source comprises a pulsator, and the control circuitry is configured to control the suction force applied by the suction source by controlling the pulsator. 11. The medical aspiration system of claim 10 , wherein the pulsator comprises a valve. 12. A method comprising: receiving, in a medical aspiration system, a signal indicative of a cardiac cycle of a patient; and controlling a suction force applied by a suction source of the medical aspiration system to a catheter to remove a thrombus from vasculature of the patient based on the signal indicative of the cardiac cycle to vary the suction force present at a distal opening of the catheter to facilitate aspiration of the thrombus from the vasculature. 13. A medical aspiration system comprising: a suction source configured to apply a suction force to a catheter to remove fluid from the catheter, wherein the catheter is configured to be navigated to a target tissue site in vasculature of a patient; and control circuitry configured to receive a signal indicative of a cardiac cycle of the patient from sensing circuitry, determine a current part of the cardiac cycle of the patient based on the signal, and control the suction force applied by the suction source to the catheter based on the determined current part of the cardiac cycle to facilitate aspiration of a thrombus from the vasculature. 14. The medical aspiration system of claim 13 , wherein the control circuitry is configured to control the suction force applied by the suction source by at least: in response to determining the current part of the cardiac cycle is diastole, controlling the suction source to apply a first suction force, and in response to determining the current part of the cardiac cycle is systole, controlling the suction source to apply a second suction force during systole, the first suction force being different from the second suction force. 15. The medical aspiration system of claim 13 , wherein the control circuitry is configured to control the suction force applied by the suction source based on the determined current part of the cardiac cycle by at least controlling the suction source to generate a first suction force at a distal opening of a catheter during a first part of the cardiac cycle and to generate a second suction force at the distal opening of the catheter during a second part of the cardiac cycle different from the first part, the second suction force being greater than the first suction force. 16. The medical aspiration system of claim 13 , further comprising sensing circuitry configured to generate a signal indicative of the cardiac cycle of the patient, wherein the control circuitry is configured to receive the signal from the sensing circuitry and determine the current part of the cardiac cycle based on the signal. 17. The medical aspiration system of claim 16 , wherein the signal comprises at least one of an electrocardiogram, an electrogram, a photoplethysmogram, or a blood pressure signal. 18. The medical aspiration system of claim 13 , further comprising the catheter fluidically coupled to the suction source, wherein the catheter comprises a flexible catheter body configured to be navigated through the vasculature of the patient. 19. The medical aspiration system of claim 13 , wherein the control circuitry is configured to control the suction force applied by the suction source to the catheter based on the determined current part of the cardiac cycle by at least cycling the suction source between an on-phase and an off-phase. 20. The medical aspiration system of claim 13 , wherein the control circuitry is configured to synchronize the application of suction force with the cardiac cycle. 21. The medical aspiration system of claim 13 , wherein the control circuitry is configured to synchronize the application of suction force with one portion of the cardiac cycle, and the application of reduced suction force or no suction force with another portion of the cardiac cycle. 22. The medical aspiration system of claim 13 , wherein the suction source comprises a pulsator, and the control circuitry is configured to control the suction force applied by the suction source by controlling the pulsator. 23. The medical aspiration system of claim 1 , wherein the control circuitry is configured to control the suction force based on the cardiac cycle to create sufficient suction force at the distal opening of the catheter to engage the thrombus with the distal opening of the catheter. 24. The medical aspiration system of claim 1 , wherein the control circuitry is configured to control the suction force based on the cardiac cycle by at least controlling the suction force to time application of a relatively high suction force to the catheter with a predetermin
specially adapted for cooperation with other devices · CPC title
Heartbeat characteristics, e.g. ECG, blood pressure modulation · CPC title
Catheters; Hollow probes (dilators A61M29/00; {peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00} ; for measuring or testing A61B; {materials for catheters A61L29/00}) · CPC title
with suction drainage system · CPC title
with suction of debris · CPC title
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