Fluid handling systems and methods

Patent metadata

Field	Value
Publication number	US-12350413-B2
Application number	US-202217846185-A
Country	US
Kind code	B2
Filing date	Jun 22, 2022
Priority date	Jun 22, 2022
Publication date	Jul 8, 2025
Grant date	Jul 8, 2025

Abstract

A dialysis system with post dialysis aseptic blood return including a fluid source, a dialyzer, a pump, a venous line, an arterial line, a bridge line coupled between the venous line and the arterial line, and a fluid source line coupled between the fluid source and a fluid port of the arterial line downstream for the bridge line. Aseptic blood return after dialysis is performed by blocking the arterial line between the bridge line and the fluid port, unblocking the bridge line, unblocking the fluid source line, and operating the pump in a forward direction to produce fluid flow from the fluid source, through the dialyzer, and through the bridge line to force venous blood in the venous line toward the patient venous access and arterial blood in the arterial line toward the patient arterial access.

First claim

What is claimed is:

1. A dialysis system comprising:
a fluid source;
a dialyzer having a venous port and an arterial port;
a pump configured to engage tubing lines;
a venous line fluidly coupled to the venous port of the dialyzer, an arterial line engaging the pump and fluidly coupled to the arterial port of the dialyzer on a first engagement side of the pump;
a bridge line coupled between the venous line and the arterial line on a second engagement side of the pump;
a fluid source line coupled between the fluid source and a fluid port of the arterial line on the second engagement side of the pump between the bridge line and the pump;
a memory configured to store program instructions; and
a processor coupled to the memory, the processor configured to process the program instructions to:
configure the dialysis system for aseptic blood return to a patient, when the patient is coupled to a patient venous access and a patient arterial access of the arterial line, by blocking the arterial line between the bridge line and the fluid port, unblocking the bridge line, and unblocking the fluid source line; and
operate the pump in a forward direction while the dialysis system is configured for aseptic blood return to produce fluid flow from the fluid source, through the dialyzer and through the bridge line, to force venous blood in the venous line toward the patient venous access and arterial blood in the arterial line toward the patient arterial access.

2. The dialysis system of claim 1 , wherein the bridge line is coupled to the venous line at a venous line connection position and to the arterial line at an arterial line connection position and wherein the venous line downstream of the venous line connection and the arterial line upstream of the arterial line connection is approximately equal in length.

3. The dialysis system of claim 1 , further comprising an air detector positioned in the venous line upstream of the bridge line.

4. The dialysis system of claim 1 , wherein an interior of the bridge line defines a volume that is between about 0.3 ml and 0.7 ml.

5. The dialysis system of claim 1 , wherein the bridge line has an inner diameter of 3.6 mm to 4.0 mm and a length of 80 mm to 100 mm.

6. The dialysis system of claim 1 , further comprising:
a first clamp configured and positioned to selectively block and unblock the fluid source line;
a second clamp configured and positioned to selectively block and unblock the arterial line between the bridge line and the fluid port, and
a third clamp configured and positioned to selectively block and unblock the bridge line.

7. The dialysis system of claim 6 , wherein the first clamp, the second clamp, and third clamp each include a selectively controllable electronic clamp and wherein the system further comprises:
a processor configured to control the selectively controllable electronic clamp of the first clamp, the second clamp, and the third clamp.

8. The dialysis system of claim 1 , further comprising:
a first clamp configured and positioned to selectively block and unblock the fluid source line; and
a three-way valve positioned within the arterial line adjacent the bridge line, the three-way valve having a first port coupled to the bridge line, a second port coupled to an upstream portion of the arterial line and a third port coupled to a downstream portion of the arterial line.

9. The dialysis system of claim 8 , wherein the three-way valve comprises:
an aseptic blood return configuration mode in which the first port is coupled to the second port and the third port is blocked;
a bridge line priming configuration mode in which the first port is coupled to the third port and the second port is blocked;
an arterial line priming configuration mode in which the first port is blocked and the second port is coupled to the third port;
a venous line priming configuration mode in which the first port is blocked and the second port is coupled to the third port; and
a therapy configuration mode in which the first port is blocked and the second port is coupled to the third port.

10. The dialysis system of claim 8 , further comprising:
a processor configured to selectively control the three-way valve.

11. The dialysis system of claim 1 , further comprising:
a memory configured to store program instructions; and
a processor coupled to the memory, the processor configured to processes the program instructions to configure the dialysis system to perform functions, including a function for:
configuring the dialysis system for priming the bridge line by blocking the arterial line between the bridge line and a patient, unblocking the arterial line between the bridge line and the fluid port, unblocking the bridge line, and unblocking the fluid source line.

12. The dialysis system of claim 1 , further comprising:
a memory configured to store program instructions; and
a processor coupled to the memory, the processor configured to processes the program instructions to configure the dialysis system to perform functions, including a function for:
configuring the dialysis system for priming the arterial line by unblocking the arterial line between the bridge line and a patient, unblocking the arterial line between the bridge line and the fluid port, blocking the bridge line, and unblocking the fluid source line.

13. The dialysis system of claim 1 , further comprising:
a memory configured to store program instructions; and
a processor coupled to the memory, the processor configured to processes the program instruction to configure the dialysis system to perform functions, including functions to:
configuring the dialysis system for priming the venous line by blocking the arterial line between the bridge line and a patient, unblocking the arterial line between the bridge line and the fluid port, blocking the bridge line, and unblocking the fluid source line:
operating the pump in a forward direction to produce fluid flow from the fluid source and through the dialyzer to force the fluid into the venous line toward the patient.

14. A fluid management method for use on a blood flow side of a dialysis system, the dialysis system comprising a fluid source, a dialyzer, a pump, a venous line fluidly coupled to a venous port of the dialyzer, an arterial line engaging the pump and fluidly coupled to an arterial port of the dialyzer on a first engagement side of the pump, a bridge line coupled between the venous line and the arterial line on a second engagement side of the pump, a fluid source line coupled between the fluid source and a fluid port of the arterial line on the second engagement side of the pump between the bridge line and the pump, a memory configured to store program instructions, and a processor coupled to the memory, the processor configured to process the program instructions to configure the dialysis system to perform steps of the method comprising:
configuring the dialysis system for aseptic blood return to a patient, when the patient is coupled to a patient venous access and a patient arterial access, by blocking the arterial line between the bridge line and the fluid port, unblocking the bridge line, and unblocking the fluid source line; and
operating the pump in a forward direction to produce fluid flow from the fluid source, through the dialyzer, and through the bridge line to force venous blood in the venous line toward the patient venous access and arterial blood in the arterial line toward the patient arterial access.

15. The method of claim 14 , further comprising the step of:
detecting air in the venous line; and
stopping the pump i

Assignees

• Braun Medical Inc

Inventors

• Ritter Kai-Uwe

Classifications

• A61M1/3649

  using dialysate as priming or rinsing liquid · CPC title

• A61M39/223

  Multiway valves · CPC title

• A61M39/28 Primary

  Clamping means for squeezing flexible tubes, e.g. roller clamps {(tube strippers A61M1/83)} · CPC title

• A61M1/1621 Primary

  Constructional aspects thereof (semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00) · CPC title

• A61M1/365

  through membranes, e.g. by inverted trans-membrane pressure [TMP] · CPC title