Inner curvature charge concentration device for tissue laceration

Patent metadata

Field	Value
Publication number	US-12349957-B2
Application number	US-201916954710-A
Country	US
Kind code	B2
Filing date	Feb 19, 2019
Priority date	Feb 22, 2018
Publication date	Jul 8, 2025
Grant date	Jul 8, 2025

Abstract

Disclosed monopolar and bipolar tissue lacerators can comprise a wire partially covered by electrical insulation, wherein the wire has a kink defining an inner curvature, wherein the wire is exposed through the insulation at one or two exposed regions along or near the inner curvature of the kink, wherein the wire is configured to conduct electrical energy through the one or two exposed regions and through a tissue target positioned adjacent the inner curvature to lacerate the tissue target via the electrical energy. The tissue target can be a native or prosthetic heart valve leaflet in a patient's heart.

First claim

The invention claimed is:

1. A focally denuded electrosurgical lacerator for use in a fluid filled region of a patient, the lacerator comprising: a wire having a proximal end and a distal end, wherein the proximal end is spaced apart from the distal end; and
wherein the wire is at least partially covered by electrical insulation and comprises a V-shaped kink having an acute angle, wherein the wire is exposed through the insulation at two continuous, exposed and non-circumferentially focally denuded regions on an inner curvature of the V-shaped kink, the continuous, exposed and non-circumferentially focally denuded regions extending less than 180 degrees around a circumference of the wire and collectively forming a cutting edge, wherein the two continuous, exposed and non-circumferentially focally denuded regions are provided proximal to and on opposing sides of the V-shaped kink, wherein the continuous, exposed and non-circumferentially focally denuded regions form a saddle operable to align the denuded regions with a tissue target, and a remainder of an inner surface of the wire is insulated, and wherein an entire length of an outer circumference of the lacerator is insulated and devoid of exposed regions to limit remote current and heat dispersion, the outer portion comprising an outer portion of the lacerator relative to the inner curvature and the cutting edge;
a radiopaque marker provided adjacent the cutting edge;
wherein at least one of the proximal end and the distal end of the wire is configured to be connected to an electrosurgical generator and the wire is configured to conduct electrical energy through and between the two continuous, exposed and non-circumferentially focally denuded regions and through the tissue target positioned between the two exposed regions in the inner curvature to lacerate the tissue target via the electrical energy.

2. The lacerator of claim 1 , wherein the electrical energy is operable to lacerate the tissue target that comprises a native heart valve leaflet or a prosthetic heart valve leaflet.

3. The lacerator of claim 1 , wherein the V-shaped kink defines an internal angle that is less than 30 degrees.

4. The lacerator of claim 1 , wherein the two exposed regions are positioned facing each other.

5. The lacerator of claim 1 , wherein the two exposed regions are positioned on opposite ends of the V-shaped kink.

6. The lacerator of claim 1 , wherein the two exposed regions each extend less than 5 mm longitudinally.

7. The lacerator of claim 1 , wherein the lacerator is operable to conduct from 50 W to 100 W of energy between the two exposed regions through the tissue target.

8. The lacerator of claim 1 , wherein the lacerator is configured to be delivered percutaneously or transvascularly into a patient's heart.

9. The lacerator of claim 1 , further comprising an irrigation catheter configured to introduce a non-ionic liquid adjacent to the two exposed regions to displace blood from around the two exposed regions.

10. A method comprising lacerating a native or prosthetic heart valve leaflet within a patient's heart using the lacerator of claim 1 .

11. The method of claim 10 , wherein the method comprises LAMPOON, BASILICA, or ELASTIC.

12. An electrosurgical lacerator for use in a fluid filled space within a patient, the lacerator comprising: a wire having a proximal end and a distal, wherein the proximal end is spaced apart from the distal end, and the wire is at least partially covered by electrical insulation, wherein the wire has a V-shaped kink defining an acute angle of less than 90 degrees, wherein the wire comprises an inner region having a cutting edge and an outer region;
the inner region comprising an inner half of a circumference of the wire on an inner curvature of the V-shaped kink;
the outer portion comprising an outer half of a circumference of the wire on an exterior portion of the V-shaped kink and provided on an opposing side of the lacerator relative to the cutting edge;
wherein the wire is exposed through the insulation along a continuous and focally denuded region solely on the inner curvature forming a cutting edge, wherein the continuous and focally denuded region is provided such that the wire is exposed on both inner sides of the V-shaped kink and wherein an entire length of the outer portion of the lacerator is insulated and devoid of exposed regions to limit remote current and heat dispersion, and wherein the continuous and focally denuded region forms a saddle operable to align the denuded region with a tissue target and a remainder of an inner surface of the wire is insulated;
wherein at least one of the proximal end and the distal end of the wire is connected to an electrosurgical generator; and
wherein the wire is configured to conduct electrical energy through the continuous and focally denuded region and through a tissue target positioned in the inner curvature to lacerate the tissue target via the electrical energy.

Assignees

• Us Health
• The Usa As Represented By The Secretary Dept Of Health And Human Services

Inventors

• Lederman Robert J
• Khan Jaffar M
• Rogers Toby

Classifications

• A61B2018/144

  Wire · CPC title

• A61B2018/141

  Snare · CPC title

• A61B18/1492

  having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence) · CPC title

• A61B2018/00083

  low, i.e. electrically insulating · CPC title

• A61B18/149

  bow shaped or with rotatable body at cantilever end, e.g. for resectoscopes, or coagulating rollers · CPC title