Engineered ligase variants

US12344872B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12344872-B2
Application numberUS-201815972919-A
CountryUS
Kind codeB2
Filing dateMay 7, 2018
Priority dateMay 8, 2017
Publication dateJul 1, 2025
Grant dateJul 1, 2025

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides engineered ligase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered ligase polypeptides. The invention also provides methods for use of the compositions comprising the engineered ligase polypeptides for diagnostic and other purposes.

First claim

Opening claim text (preview).

What is claimed is: 1. An engineered T4 DNA ligase comprising a polypeptide sequence, wherein the polypeptide sequence consists of SEQ ID NO:38.

Assignees

Inventors

Classifications

  • DNA ligase (ATP) (6.5.1.1) · CPC title

  • Polynucleotides, e.g. nucleic acids, oligoribonucleotides · CPC title

  • Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay (C12Q1/6804 takes precedence) · CPC title

  • Massive parallel sequencing · CPC title

  • incorporating an adaptor · CPC title

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Frequently asked questions

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What does patent US12344872B2 cover?
The present invention provides engineered ligase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered ligase polypeptides. The invention also provides methods for use of the compositions comprising the engineered ligase polypeptides for diagnostic and other purposes.
Who is the assignee on this patent?
Codexis Inc
What technology area does this patent fall under?
Primary CPC classification C12N9/93. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).