Method for producing cysteine from glutathione

US12344871B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12344871-B2
Application numberUS-202017597231-A
CountryUS
Kind codeB2
Filing dateJun 17, 2020
Priority dateJul 2, 2019
Publication dateJul 1, 2025
Grant dateJul 1, 2025

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

It is an object of the present invention to provide a practical means of producing cysteine from glutathione that is also suitable for use in the field of foods. Cysteine is produced from glutathione by a first step of producing cysteinylglycine by the action of a γ-glutamyl peptidase derived from a microorganism on reduced glutathione; and a second step of producing cysteine by the action of an acid protease derived from a microorganism on the cysteinylglycine.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for producing cysteine from glutathione comprising: adding a glutaminase derived from Bacillus amyloliquefaciens and an acid protease derived from Aspergillus oryzae to a glutathione-containing composition or a solution thereof, or a glutathione solution; a first step of producing cysteinylglycine by reacting the glutaminase derived from Bacillus amyloliquefaciens on the glutathione-containing composition or a solution thereof, or a glutathione solution to produce cysteinylglycine; and a second step of producing cysteine by reacting the acid protease derived from Aspergillus oryzae on the cysteinylglycine, wherein the first step and the second step are simultaneously performed, and wherein the first and second reactions are carried out at a pH of 4 to 6. 2. The method according to claim 1 , wherein the glutathione-containing composition is meat, a processed meat product, seafood, a processed seafood product, a vegetable, a processed vegetable product, yeast extract, or meat extract.

Assignees

Inventors

Classifications

  • Gamma-glutamyltransferase (2.3.2.2) · CPC title

  • having a known sequence of two or more amino acids, e.g. glutathione · CPC title

  • C12P13/12Primary

    Methionine; Cysteine; Cystine · CPC title

  • from Aspergillus · CPC title

  • bacteria being Bacillus · CPC title

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What does patent US12344871B2 cover?
It is an object of the present invention to provide a practical means of producing cysteine from glutathione that is also suitable for use in the field of foods. Cysteine is produced from glutathione by a first step of producing cysteinylglycine by the action of a γ-glutamyl peptidase derived from a microorganism on reduced glutathione; and a second step of producing cysteine by the action of a…
Who is the assignee on this patent?
Amano Enzyme Inc, Amano Enzyme Europe Ltd
What technology area does this patent fall under?
Primary CPC classification C12P13/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).