Devices, systems, and methods for estimating active medication from injections

Patent metadata

Field	Value
Publication number	US-12343495-B2
Application number	US-202217806896-A
Country	US
Kind code	B2
Filing date	Jun 14, 2022
Priority date	Dec 12, 2017
Publication date	Jul 1, 2025
Grant date	Jul 1, 2025

Abstract

One or more embodiments relate, generally, to a reusable accessory for a medication injection pen. Such a reusable accessory may be adapted to be reversibly attached to a medication injection pen, and configured to detect an event associated with an injection of medication from the medication injection pen. It may also be configured to determine a percentage of medication that remains active for injection by the medication injection pen based on timing information and dosing event information.

First claim

What is claimed is:

1. An accessory for an injection pen, the accessory comprising:
a display configured to indicate information regarding therapy to a user; and
a controller comprising:
at least one processor; and
at least one non-transitory computer-readable storage medium storing instructions thereon that, when executed by the at least one processor, cause the controller to perform operations comprising:
detecting dosing events associated with the injection pen; and
responsive to a most recent dosing event, changing a displayed appearance of the display from a first displayed appearance to a second displayed appearance.

2. The accessory of claim 1 , wherein detecting dosing events associated with the injection pen comprises detecting at least one of a capping or a decapping event of the accessory relative to the injection pen.

3. The accessory of claim 1 , wherein the operations further comprise:
responsive to a time since the most recent dosing event exceeding a threshold period of time, changing a displayed appearance of the display from the second displayed appearance to a third displayed appearance.

4. The accessory of claim 3 , wherein the threshold period of time comprises a range 3 hours to 6 hours.

5. The accessory of claim 3 , wherein the threshold period of time comprises a rang of 6 hours to 12 hours.

6. The accessory of claim 1 , wherein the first displayed appearance of the one or more indicators indicates that an insufficient amount of time has passed since a most recent dosing event to warrant an additional dose.

7. The accessory of claim 1 , further comprising an adapter configured to couple the accessory to the injection pen.

8. The accessory of claim 1 , wherein the accessory comprises a pen cap.

9. The accessory of claim 1 , wherein changing the displayed appearance from the first displayed appearance to the second displayed appearance comprises changing a color of at least a portion of the display.

10. The accessory of claim 1 , wherein the operations further comprise:
receiving glucose data collected from a glucose monitor.

11. The accessory of claim 10 , wherein the operations further comprise:
displaying the glucose data on the display of the accessory.

12. The accessory of claim 1 , wherein the accessory is configured to be utilized with one or more of a long-acting insulin pen or a rapid-acting insulin pen.

13. The accessory of claim 1 , wherein the operations further comprise:
receiving patient-specific therapy parameters.

14. The accessory of claim 13 , wherein the patient-specific therapy parameters comprise one or more of dose parameters or timing parameters.

15. The accessory of claim 13 , wherein the patient-specific therapy parameters are configured to be received from remote device.

16. The accessory of claim 1 , wherein the operations further comprise:
communicating dosing data to an application.

17. The accessory of claim 1 , wherein the operations further comprise:
communicating dosing data via a wireless communication protocol.

18. The accessory of claim 1 , wherein the operations further comprise:
wirelessly pairing the accessory with a remote device.

19. The accessory of claim 1 , wherein the operations further comprise:
responsive to the accessory being capped on or uncapped from the injection pen for at least a threshold period of time, inferring a dosing event.

20. The accessory of claim 1 , wherein the operations further comprise:
responsive to the accessory being capped on or uncapped from the injection pen for less than a threshold period of time, determining that a dosing event has not occurred.

21. The accessory of claim 1 , wherein the operations further comprise:
receiving a manual input indicating a dosing event.

22. The accessory of claim 1 , wherein the operations further comprise:
determining a time associated with a previous capping or decapping of the accessory; and
outputting a notification that active insulin remains within the user based on a current time and the time associated with the previous capping or decapping of the accessory.

23. A pen cap for a medication delivery device, the pen cap comprising:
an indicator configured to indicate therapy data to a user;
a controller comprising:
at least one processor; and
at least one non-transitory computer-readable storage medium storing instructions thereon that, when executed by the at least one processor, cause the pen cap to perform operations comprising:
detecting attachment of the pen cap to the medication delivery device or detachment of the pen cap from the medication delivery device; and
responsive to the pen cap being attached to or detached from the medication delivery device, changing a displayed appearance of at least a portion of the indicator from a first displayed appearance to a second displayed appearance.

24. The pen cap of claim 23 , wherein the operations further comprise:
responsive to the pen cap being attached to or detached from the medication delivery device for a threshold period of time, changing an appearance of the at least a portion of the indicator from the second displayed appearance to a third appearance.

25. The pen cap of claim 24 , wherein the threshold period of time comprises a range of 3 hours to 6hours.

26. The pen cap of claim 24 , wherein the threshold period of time comprises a range of 6 hours to 12 hours.

27. The pen cap of claim 23 , wherein the second displayed appearance of the at least a portion of the indicator indicates that an insufficient amount of time has passed since a previous dosing event.

28. The pen cap of claim 23 , further comprising an adapter configured to removably attach the pen cap to the medication delivery device.

29. The pen cap of claim 23 , wherein the pen cap comprises a universal pen cap configured to be removably attachable to multiple medication delivery devices.

30. The pen cap of claim 23 , wherein changing the displayed appearance from the first displayed appearance to the second displayed appearance comprises changing a color of the at least a portion of the indicator.

31. The pen cap of claim 23 , wherein the operations further comprise:
receiving glucose data collected from an in vivo glucose monitoring device.

32. The pen cap of claim 31 , wherein the operations further comprise:
displaying the glucose data on the indicator of the pen cap.

33. The pen cap of claim 23 , wherein the pen cap is configured to be attachable to one or more of a long-acting insulin pen or a rapid-acting insulin pen.

34. The pen cap of claim 23 , wherein the operations further comprise:
receiving patient-specific therapy parameters.

35. The pen cap of claim 34 , wherein the patient-specific therapy parameters comprise one or more of dose parameters or timing parameters.

36. The pen cap of claim 34 , wherein the patient-specific therapy parameters are configured to be received from a remote device.

37. The pen cap of claim 23 , wherein the operations further comprise:
communicating dosing data to an application on a remote device.

38. The pen cap of claim 23 , wherein the operations further comprise:
communicating dosing data via a

Assignees

• Bigfoot Biomedical Inc

Inventors

• Sjolund John
• Srinath Ambika
• Bochenko Andrew
• Crothall George
• Mazlish Bryan
• Block Jennifer Martin
• Matarese Sarah
• Mackowiak Linda
• Desborough Lane

Classifications

• A61B5/7455

  characterised by tactile indication, e.g. vibration or electrical stimulation · CPC title

• A61M2205/3584

  using modem, internet or Bluetooth® · CPC title

• A61M2205/3306

  Optical measuring means · CPC title

• A61M2005/2006

  Having specific accessories · CPC title

• A61M5/3202

  Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001) · CPC title