Imipramine for use as an inhibitor of Fascin1 overexpression

US12343349B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12343349-B2
Application numberUS-201917281084-A
CountryUS
Kind codeB2
Filing dateSep 22, 2019
Priority dateSep 28, 2018
Publication dateJul 1, 2025
Grant dateJul 1, 2025

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention refers to Imipramine for use as inhibitor of fascin1 overexpression, preferably said overexpression of fascin1 is associated to cancer, and more preferably to colorectal cancer. It also refers to a method for the treatment of cancer mediated by fascin1 comprising administering to a subject in need thereof an effective amount of imipramine, and more preferably to colorectal cancer.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for the treatment of cancer mediated by fascin1 comprising administering to a subject in need thereof an effective amount of imipramine. 2. The method according to claim 1 , wherein the fascin1 is overexpressed. 3. The method according to claim 1 , wherein the cancer is colorectal cancer. 4. The method according to claim 3 , wherein the colorectal cancer is serrated adenocarcinoma. 5. The method according to claim 3 , wherein the colorectal cancer is selected from gastrointestinal stromal tumors, leiomyosarcomas or melanomas. 6. The method according to claim 3 , wherein the colorectal cancer is metastatic colorectal cancer.

Assignees

Inventors

Classifications

  • Antineoplastic agents · CPC title

  • A61K31/55Primary

    having seven-membered rings, e.g. azelastine, pentylenetetrazole · CPC title

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What does patent US12343349B2 cover?
The present invention refers to Imipramine for use as inhibitor of fascin1 overexpression, preferably said overexpression of fascin1 is associated to cancer, and more preferably to colorectal cancer. It also refers to a method for the treatment of cancer mediated by fascin1 comprising administering to a subject in need thereof an effective amount of imipramine, and more preferably to colorectal…
Who is the assignee on this patent?
Fundacion Univ San Antonio, Fundacion Para La Formacion E Investig Sanitarias, Univ Granada
What technology area does this patent fall under?
Primary CPC classification A61K31/55. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).