Methods and apparatus for treating embolism

Patent metadata

Field	Value
Publication number	US-12343028-B2
Application number	US-202418438336-A
Country	US
Kind code	B2
Filing date	Feb 9, 2024
Priority date	Oct 21, 2013
Publication date	Jul 1, 2025
Grant date	Jul 1, 2025

Abstract

A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

First claim

We claim:

1. A method of treating clot material in a blood vessel, the method comprising:
advancing a clot treatment device in a low-profile state through a lumen of a guide catheter, wherein the clot treatment device includes a mesh structure and a plurality of treatment portions;
at least partially expanding the clot treatment device within the blood vessel from the low-profile state to a deployed state, wherein individual ones of the treatment portions include a proximally-facing curved portion and a distally-facing curved portion in the deployed state, and wherein the proximally-facing curved portion and the distally-facing curved portion have a same radius of curvature;
engaging the clot treatment device with the clot material; and
retracting the clot treatment device and a portion of the clot material into a distal portion of the guide catheter.

2. The method of claim 1 wherein at least partially expanding the clot treatment device within the blood vessel comprises at least partially expanding (a) a first one of the treatment portions distal of the clot material and (b) a second one of the treatment portions within the clot material.

3. The method of claim 1 wherein the treatment portions are formed from the mesh structure.

4. The method of claim 1 wherein the clot material comprises a pulmonary embolism, and wherein the blood vessel comprises a pulmonary blood vessel.

5. The method of claim 1 wherein the clot material comprises a deep vein thrombosis, and wherein the blood vessel comprises a peripheral vein.

6. The method of claim 1 wherein the method further comprises aspirating the lumen of the guide catheter.

7. The method of claim 6 wherein aspirating the lumen of the guide catheter comprises actuating a syringe fluidly coupled to the lumen of the guide catheter.

8. The method of claim 6 wherein aspirating the lumen of the guide catheter comprises providing discrete pulses of aspiration to the lumen of the guide catheter.

9. The method of claim 6 wherein aspirating the lumen of the guide catheter comprises aspirating the lumen of the guide catheter before retraction of the clot treatment device and the portion of the clot material into the distal portion of the guide catheter.

10. The method of claim 9 wherein aspirating the lumen of the guide catheter comprises actuating a syringe.

11. The method of claim 6 wherein aspirating the lumen of the guide catheter comprises aspirating less than about 200 cubic centimeters of blood and the portion of the clot material from the blood vessel.

12. The method of claim 6 wherein aspirating the lumen of the guide catheter comprises aspirating less than about 100 cubic centimeters of blood and the portion of the clot material from the blood vessel.

13. The method of claim 1 wherein at least partially expanding the clot treatment device within the blood vessel comprises moving the guide catheter relative to the clot treatment device to permit the clot treatment device to self-expand within the blood vessel from the low-profile state to the deployed state.

14. The method of claim 1 wherein advancing the clot treatment device through the lumen of the guide catheter comprises advancing an elongated shaft having a distal portion coupled to the clot treatment device.

15. The method of claim 14 wherein at least partially expanding the clot treatment device within the blood vessel comprises at least partially expanding the clot treatment device in a direction radially away from the elongated shaft.

16. A system for intravascularly treating clot material in a blood vessel, comprising:
a guide catheter having a lumen;
an elongated shaft configured to extend through the guide catheter; and
a clot treatment device coupled to a distal portion of the elongated shaft, wherein the clot treatment device includes a mesh structure and a plurality of treatment portions, wherein the clot treatment device is radially expandable from (a) a low-profile state in which the clot treatment device is sized for delivery to the clot material through the lumen of the guide catheter to (b) a deployed state in which the clot treatment device is configured to engage the clot material, and wherein in the deployed state—
individual ones of the treatment portions include a proximally-facing curved portion and a distally-facing curved portion, and
the proximally-facing curved portion and the distally-facing curved portion have a same radius of curvature.

17. The system of claim 16 , further comprising a pump mechanism configured to be fluidly coupled to the lumen of the guide catheter and to aspirate the lumen of the guide catheter.

18. The system of claim 17 wherein the pump mechanism is configured to provide discrete pulses of aspiration to the lumen of the guide catheter.

19. The system of claim 18 wherein the pump mechanism comprises a syringe.

20. The system of claim 17 wherein the pump mechanism comprises a syringe configured to aspirate less than about 100 cubic centimeters of blood and the clot material from the blood vessel.

Assignees

• Inari Medical Inc

Inventors

• Cox Brian J
• Lubock Paul
• Rosenbluth Robert
• Quick Richard
• Marchand Philippe

Classifications

• A61B17/22

  Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for · CPC title

• A61M25/10

  Balloon catheters ({A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02;} inflatable balloons for placing stents or stent-grafts A61F2/958 {; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00}) · CPC title

• A61M25/0662

  Guide tubes · CPC title

• A61M2025/1004

  Balloons with folds, e.g. folded or multifolded · CPC title

• A61M2025/1047

  having centering means, e.g. balloons having an appropriate shape · CPC title