P-wave detection using intracardiac electrodes

Patent metadata

Field	Value
Publication number	US-12336832-B2
Application number	US-202217692232-A
Country	US
Kind code	B2
Filing date	Mar 11, 2022
Priority date	Mar 11, 2022
Publication date	Jun 24, 2025
Grant date	Jun 24, 2025

Abstract

A method includes acquiring intracardiac unipolar signals and intracardiac bipolar signals at a given region of a heart of a patient. The unipolar signals are pruned by eliminating ones of the unipolar signals that correspond in time to respective bipolar signals. One or more unipolar signals are identified among the pruned unipolar signals, that are associated with far-field P-waves. Using the identified P-waves, a window of interest (WOI) is set on electrograms acquired in an atrium of the heart, and, using the electrograms having the set WOI, an electrophysiological (EP) map is generated, of the atrium indicative of atrial tachycardia (AT) tissue locations therein.

First claim

The invention claimed is:

1. A method to identify and annotate a P-wave during EP mapping, comprising:
acquiring intracardiac unipolar signals and intracardiac bipolar signals at a given region of a heart of a patient, wherein the given region is one of a superior vena cava (SVC) and an inferior vena cava (IVC);
removing a QRS complex from the unipolar signals and the bipolar signals;
detecting unipolar activations, of remaining unipolar signals remaining after the QRS complex removal, occurring at first points in time based on a first predetermined electrical activation value threshold;
detecting bipolar activations, of remaining bipolar signals remaining after the QRS complex removal, occurring at second points in time based on a second predetermined electrical activation value threshold;
pruning the remaining unipolar signals, by eliminating ones of the remaining unipolar signals that correspond in time to respective bipolar signals;
identifying, among the pruned unipolar signals, one or more unipolar signals that are associated with far-field P-waves; and
using the identified far-field P-waves, setting a window of interest (WOI) on electrograms acquired in an atrium of the heart, and generating, using the electrograms having the set WOI, an electrophysiological (EP) map of the atrium indicative of atrial tachycardia (AT) tissue locations therein,
wherein identifying the one or more unipolar signals that are associated with the far-field P-waves comprises weighting the pruned unipolar signals based on a timing of occurrence of the unipolar signals relative to the QRS complex, and
wherein setting the WOI comprises adding annotations of the far-field P-waves on the electrograms and using the annotations as a time reference of the WOI.

2. The method according to claim 1 , wherein the given region is a blood pool of the atrium.

3. The method according to claim 1 , wherein identifying the one or more unipolar signals that are associated with the far-field P-waves comprises further weighting the pruned unipolar signals based on a number of heart cycles over which the unipolar signals have been acquired.

4. The method according to claim 1 , wherein acquiring the unipolar signals and the bipolar signals is performed using a catheter fitted with electrodes.

5. The method according to claim 1 , wherein the EP map is a local activation time (LAT) map.

6. A system to identify and annotate a P-wave during EP mapping, comprising:
a memory configured to store intracardiac unipolar signals and bipolar signals acquired at a given region of a heart of a patient, wherein the given region is one of a superior vena cava (SVC) and an inferior vena cava (IVC); and
a processor, which is configured to:
remove a QRS complex from the unipolar signals and the bipolar signals;
detect unipolar activations, of remaining unipolar signals remaining after the QRS complex removal, occurring at first points in time based on a first predetermined electrical activation value threshold;
detect bipolar activations, of remaining bipolar signals remaining after the QRS complex removal, occurring at second points in time based on a second predetermined electrical activation value threshold;
prune the remaining unipolar signals by eliminating ones of the remaining unipolar signals that correspond in time to respective bipolar signals;
identify, among the pruned unipolar signals, one or more unipolar signals that are associated with far-field P-waves; and
use the identified far-field P-waves, set a window of interest (WOI) on electrograms acquired in an atrium of the heart, and generate, using the electrograms having the set WOI, an electrophysiological (EP) map of the atrium indicative of atrial tachycardia (AT) tissue locations therein,

wherein the processor is configured to identify the one or more unipolar signals that are associated with the far-field P-waves by weighting the pruned unipolar signals based on a timing of occurrence of the unipolar signals relative to the QRS complex, and
wherein setting the WOI comprises adding annotations of the far-field P-waves on the electrograms and using the annotations as a time reference of the WOI.

7. The system according to claim 6 , wherein the given region is a blood pool of the atrium.

8. The system according to claim 6 , wherein the processor is configured to identify the one or more unipolar signals that are associated with the far-field P-waves by further weighting the pruned unipolar signals based on a number of heart cycles over which the unipolar signals have been acquired.

9. The system according to claim 6 , wherein the unipolar signals and the bipolar signals are acquired using a catheter fitted with electrodes.

10. The system according to claim 6 , wherein the EP map is a local activation time (LAT) map.

11. The method according to claim 1 , further comprising:
detecting the unipolar activations, of the remaining unipolar signals, occurring at the first points in time when a voltage derivative of the remaining unipolar signals is above the first predetermined electrical activation value threshold; and
detecting the bipolar activations, of the remaining bipolar signals, occurring at the second points in time when at least one of a voltage derivative of the remaining bipolar signals or an absolute value of a voltage amplitude of the remaining bipolar signals is above the second predetermined electrical activation value threshold.

Assignees

• Biosense Webster Israel Ltd

Inventors

• Wolff Marc
• Nakar Elad
• Ravuna Eliyahu
• Yanovich Nir
• Reuveny Hadar

Classifications

• A61B5/7235

  Details of waveform analysis (detecting specific parameters of the electrocardiograph cycle A61B5/349) · CPC title

• A61B5/367 Primary

  Electrophysiological study [EPS], e.g. electrical activation mapping or electro-anatomical mapping · CPC title

• A61B5/283

  Invasive · CPC title

• A61B2018/00357

  Endocardium · CPC title

• A61B2018/00577

  Ablation · CPC title