Medicament delivery device

Patent metadata

Field	Value
Publication number	US-12329941-B2
Application number	US-201917293161-A
Country	US
Kind code	B2
Filing date	Nov 20, 2019
Priority date	Dec 20, 2018
Publication date	Jun 17, 2025
Grant date	Jun 17, 2025

Abstract

A medicament delivery device is presented having a housing with a proximal end and a distal end, a multi-chamber container arranged in the housing, a power assembly having accumulated energy arranged in the housing and configured to act on the multi-chamber container for obtaining and delivering a blended compound inside the multi-chamber container and a manually operable assembly extending from the distal end of the housing and being connected with the power assembly, wherein upon a manual movement of the manually operable assembly the power assembly is forced to move towards the proximal end to pressurize the multi-chamber container and wherein the medicament delivery device further comprises a needle shield sleeve slidably arranged in the housing, the needle shield sleeve being configured to interact with the power assembly to release the accumulated energy after the power assembly has been moved towards the proximal end.

First claim

The invention claimed is:

1. A medicament delivery device comprising:
a housing having a proximal end and a distal end;
a multi-chamber container arranged in the housing;
a container holder axially and rotationally fixed to the housing and in which the multi-chamber container is accommodated;
a power assembly having accumulated energy, arranged in the housing and configured to act on the multi-chamber container for obtaining and delivering a blended compound inside the multi-chamber container, wherein a portion of the power assembly is axially fixed in the housing; and
a manually operable assembly extending from the distal end of the housing and being connected with the power assembly,
wherein the manually operable assembly is connected with the portion of the power assembly that is axially fixed in the housing by a threaded connection,
wherein upon a manual movement of the manually operable assembly, the power assembly is forced to move towards the proximal end to pressurize the multi-chamber container, and
wherein the medicament delivery device further comprises a needle shield sleeve slidably arranged in the housing, the needle shield sleeve being configured to interact with the power assembly to release the accumulated energy after the power assembly has been moved towards the proximal end.

2. The medicament delivery device according to claim 1 , wherein the power assembly is a gas driven power assembly, an electromechanical driven power assembly, or a spring driven power assembly.

3. The medicament delivery device according to claim 1 , wherein the manual movement of the manually operable assembly is a rotational movement and the threaded connection is configured to cause a linear movement of the power assembly towards the proximal end.

4. The medicament delivery device according to claim 1 , comprising a resilient member arranged between a proximal end of the container holder and a proximal inner ledge of the needle shield sleeve.

5. The medicament delivery device according to claim 4 , comprising a needle assembly disposed on the proximal end of the container holder and having a needle, wherein the multi-chamber container has a septum, and wherein the needle assembly is configured to be manually manipulated to move the needle toward the multi-chamber container in order for a distal end of the needle to pierce the septum.

6. The medicament delivery device according to claim 5 , wherein the needle assembly comprises:
a needle hub fixedly connected to the needle;
an inner cap configured to move the needle hub;
a retainer fixedly connected to the container holder and interactively engaged with the needle hub; and
a manually operable outer cap configured to move the inner cap whereby the inner cap in turn moves the needle hub through the retainer and toward the multi-chamber container in order for the distal end of the needle to pierce the septum and whereby the inner cap together with the manually operable outer cap can be removed from the rest of the medicament delivery device.

7. The medicament delivery device according to claim 6 , wherein the manually operable outer cap is configured to lock the needle shield sleeve in an initial locked position in which the needle shield sleeve is prevented from being axially moveable by a bias of the resilient member towards a proximal end of the medicament delivery device to an initial unlocked position.

8. The medicament delivery device according to claim 7 , wherein a member on a distal end of the needle shield sleeve is releasably locked to a member of the manually operable assembly when the needle shield sleeve is in the initial locked position for preventing the manually operable assembly to be manually operated.

9. The medicament delivery device according to claim 8 , wherein upon removal of the manually operable outer cap from the medicament delivery device, the needle shield sleeve is forced by the bias of the resilient member to move a predetermined distance in relation to the housing from the initial locked position to the initial unlocked position in which a predetermined portion of the needle shield sleeve protrudes from the proximal end of the housing.

10. The medicament delivery device according to claim 9 , wherein a movement of the needle shield sleeve in relation to the housing from the initial unlocked position towards the distal end of the housing allows the member on the distal end of the needle shield sleeve to interact with a member of the power assembly to release the accumulated energy in the power assembly.

11. The medicament delivery device according to claim 1 , wherein the multi-chamber container comprises a stopper and the power assembly comprises a plunger rod configured to be in contact with a distal surface of the stopper.

12. The medicament delivery device according to claim 11 , wherein the power assembly further comprises a holding and release unit configured to interact with the plunger rod and the needle shield sleeve for holding and releasing the accumulated energy in the power assembly.

13. The medicament delivery device according to claim 12 , wherein the holding and release unit is the portion of the power assembly that is axially fixed in the housing.

14. The medicament delivery device according to claim 1 , wherein the housing comprises one or more radial openings, and wherein the container holder comprises one or more radially outward extending locking members such that the one or more radially outward extending locking members are configured to be received in the one or more radial openings.

15. A medicament delivery device comprising:
a housing having a proximal end and a distal end;
a multi-chamber container arranged in the housing;
a container holder axially and rotationally fixed to the housing and in which the multi-chamber container is accommodated;
a needle shield sleeve slidably arranged in the housing;
a power assembly having accumulated energy, arranged in the housing and configured to act on the multi-chamber container for obtaining and delivering a blended compound inside the multi-chamber container, wherein a portion of the power assembly is axially fixed in the housing; and
a manually operable assembly extending from the distal end of the housing and being connected with the power assembly,
wherein the manually operable assembly is connected with the portion of the power assembly that is axially fixed in the housing by a threaded connection,
wherein a rotational movement of the manually operable assembly by a user of the medicament delivery device causes linear movement of the power assembly towards the proximal end to pressurize the multi-chamber container, and
wherein the needle shield sleeve is configured to interact with the power assembly to release the accumulated energy after the power assembly has moved towards the proximal end.

16. The medicament delivery device according to claim 15 further comprising a resilient member arranged between a proximal end of the container holder and a proximal inner ledge of the needle shield sleeve.

17. A medicament delivery device comprising:
a housing having a proximal end and a distal end;
a multi-chamber container arranged in a container holder axially fixed inside the housing;
a needle shield sleeve slidably arranged in the housing;
a needle assembly disposed on a proximal end of the container holder and having a needle,
a power assembly having accumulated energy, arranged in the housing and configured to act on the multi-chamber container for obtaining and delivering a blended compound inside the multi-cha

Assignees

• Shl Medical Ag

Inventors

• Ratjen Jochen

Classifications

• A61M2005/3268

  having cantilever elastically spreadable arms, e.g. to accumulate energy during needle uncovering movement for urging protection sleeve to return to needle covering position · CPC title

• A61M2005/2474

  with movable piercing means, e.g. ampoule remains fixed or steady · CPC title

• A61M2005/2451

  preventing delivery before mixing is completed, e.g. by locking mechanisms · CPC title

• A61M5/3202

  Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001) · CPC title

• A61M5/2046

  Media being expelled from injector by gas generation, e.g. explosive charge · CPC title