Zirconia-based porous body and method for producing same
US-9956543-B2 · May 1, 2018 · US
Porous zirconia particles, and aggregate for immobilizing protein
US12325642B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12325642-B2 |
| Application number | US-202017424640-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 17, 2020 |
| Priority date | Jan 24, 2019 |
| Publication date | Jun 10, 2025 |
| Grant date | Jun 10, 2025 |
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Abstract
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Porous zirconia particles exhibit high specificity to a protein to be immobilized thereto and are used in immobilization of the protein. The porous zirconia particles have a pore diameter D50, at which a ratio of a cumulative pore volume to a total pore volume is 50%, the pore diameter D50 being in a range of 3.20 nm or more and 6.50 nm or less; and a pore diameter D90, at which a ratio of a cumulative pore volume to a total pore volume is 90%, the pore diameter D90 being in a range of 10.50 nm or more and 100.00 nm or less. The total pore volume of the particles is greater than 0.10 cm 3 /g. D50, D90, and the total pore volume are determined based on a pore diameter distribution measured through a BET method.
First claim
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The invention claimed is: 1. Porous zirconia particles for immobilization of a protein, characterized in that the porous zirconia particles have: a pore diameter D50, at which a ratio of a cumulative pore volume to a total pore volume is 50%, is in a range of 3.20 nm or more and 6.50 nm or less; and a pore diameter D90, at which a ratio of a cumulative pore volume to the total pore volume is 90%, is in a range of 10.50 nm or more and 100.00 nm or less, wherein the total pore volume is greater than 0.10 cm 3 /g, and wherein the pore diameter D50, the pore diameter D90, and the total pore volume are determined based on a pore diameter distribution measured through a BET method. 2. The porous zirconia particles according to claim 1 , wherein the protein is immunoglobulin. 3. The porous zirconia particles according to claim 2 , wherein the immunoglobulin is at least one species selected from the group consisting of IgG, IgE, and IgD. 4. The porous zirconia particles according to claim 1 , wherein the porous zirconia particles have surfaces onto which a chelating agent is bound.
Assignees
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Classifications
Pore diameter distribution · CPC title
Pore volume · CPC title
Use of binding agents; addition of materials ameliorating the mechanical properties of the produced sorbent · CPC title
Pore-size distribution · CPC title
Pore diameter · CPC title
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- What does patent US12325642B2 cover?
- Porous zirconia particles exhibit high specificity to a protein to be immobilized thereto and are used in immobilization of the protein. The porous zirconia particles have a pore diameter D50, at which a ratio of a cumulative pore volume to a total pore volume is 50%, the pore diameter D50 being in a range of 3.20 nm or more and 6.50 nm or less; and a pore diameter D90, at which a ratio of a cu…
- Who is the assignee on this patent?
- Ngk Spark Plug Co, Aist, Niterra Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C01G25/02. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).