Compositions for identification of membrane targets for enhancement of T cell activity against cancer

US12297428B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12297428-B2
Application numberUS-201917264691-A
CountryUS
Kind codeB2
Filing dateJul 31, 2019
Priority dateAug 1, 2018
Publication dateMay 13, 2025
Grant dateMay 13, 2025

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention includes compositions and methods for identification of membrane targets for enhancement of T cell activity against a disease, disorder or condition, and/or enhancing T cell anti-tumor activity in a subject in need thereof. In some embodiments, the disease is cancer. In further embodiments, the cancer is glioblastoma (GBM) or breast cancer.

First claim

Opening claim text (preview).

What is claimed is: 1. An adeno-associated virus (AAV) vector comprising the nucleic acid sequence set forth in SEQ ID NO: 69,821.

Assignees

Inventors

Classifications

  • Epidermal growth factor receptors [EGFR] · CPC title

  • Cancer antigens · CPC title

  • Chimeric antigen receptors [CAR] · CPC title

  • T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells · CPC title

  • characterized by the route of administration · CPC title

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What does patent US12297428B2 cover?
The present invention includes compositions and methods for identification of membrane targets for enhancement of T cell activity against a disease, disorder or condition, and/or enhancing T cell anti-tumor activity in a subject in need thereof. In some embodiments, the disease is cancer. In further embodiments, the cancer is glioblastoma (GBM) or breast cancer.
Who is the assignee on this patent?
Univ Yale
What technology area does this patent fall under?
Primary CPC classification C12N15/111. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue May 13 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).