Inverting thrombectomy apparatuses having enhanced tracking

Patent metadata

Field	Value
Publication number	US-12295601-B2
Application number	US-202318386930-A
Country	US
Kind code	B2
Filing date	Nov 3, 2023
Priority date	Nov 9, 2017
Publication date	May 13, 2025
Grant date	May 13, 2025

Abstract

Mechanical thrombectomy apparatuses, and particularly knitted rolling tube mechanical thrombectomy apparatuses configured to have improved tracking for delivery through tortious vessels are described herein. Also described herein are methods of removing clots using a mechanical thrombectomy apparatuses in which the clot is larger than the tractor portion of the mechanical thrombectomy apparatus.

First claim

The invention claimed is:

1. A thrombectomy catheter system, comprising:
an inversion support catheter having an outer surface, a distal end, and a lumen;
a first inverting flexible tube sub-assembly loaded onto the inversion support catheter, the first inverting flexible tube sub-assembly including a first flexible tube and a first puller coupled to the first flexible tube;
wherein the first inverting flexible tube sub-assembly is configured to be removed from the inversion support catheter;
a second inverting flexible tube sub-assembly, the second inverting flexible tube sub-assembly including a second flexible tube and a second puller coupled to the second flexible tube;
wherein the second inverting flexible tube sub-assembly is configured to be loaded onto the inversion support catheter after the first inverting flexible tube sub-assembly is removed from the inversion support catheter, wherein the second inverting flexible tube sub-assembly is configured to be advanced through the distal end of the inversion support catheter and into the lumen, and a portion of the second inverting flexible tube sub-assembly inverts over the distal end of the inversion support catheter and extends along the outer surface of the inversion support catheter;
wherein the first inverting flexible tube sub-assembly further comprises a cuff;
wherein the cuff is slidable along the inversion support catheter; and
wherein the cuff is configured to split apart when the cuff reaches a distal end of the inversion support catheter.

2. The thrombectomy catheter system of claim 1 , wherein the second inverting flexible tube sub-assembly further comprises a cuff.

3. The thrombectomy catheter system of claim 2 , wherein the cuff is configured to slide proximally along the inversion support catheter when the second inverting flexible tube sub-assembly is loaded onto the inversion support catheter.

4. The thrombectomy catheter system of claim 1 , further comprising an intermediate catheter configured to be disposed about the inversion support catheter.

5. The thrombectomy catheter system of claim 4 , wherein the intermediate catheter is configured to couple with a vacuum source to apply vacuum between the intermediate catheter and the inversion support catheter.

6. The thrombectomy catheter system of claim 1 , wherein the first flexible tube comprises a knitted flexible tube having a plurality of interlocking loops.

7. The thrombectomy catheter system of claim 1 , wherein the first flexible tube is configured to be pulled proximally into the inversion support catheter by pulling the first puller proximally so that the first flexible tube inverts over a distal end of the inversion support catheter.

8. The thrombectomy catheter system of claim 1 , wherein one or more regions of the first flexible tube are configured to be held against an outer surface of the inversion support catheter to maintain the first flexible tube in a compressed state.

9. A method for reloading an inverting tube apparatus, the method comprising:
proximally retracting a first inverting flexible tube sub-assembly from an inversion support catheter;
wherein the inversion support catheter includes an outer surface, a distal end, and a lumen;
wherein the first inverting flexible tube sub-assembly includes a first flexible tube and a first puller coupled to the first flexible tube;
wherein the first inverting flexible tube sub-assembly includes a cuff;
wherein the cuff is slidable along the inversion support catheter;
wherein the cuff is configured to split apart when the cuff reaches a distal end of the inversion support catheter;
loading a second inverting flexible tube sub-assembly onto the inversion support catheter, wherein loading the second inverting flexible tube sub-assembly onto the inversion support catheter includes advancing the second inverting flexible tube sub-assembly through the distal end of the inversion support catheter and into the lumen and inverting the second inverting flexible tube sub-assembly over the distal end of the inversion support catheter so that a portion of the second inverting flexible tube sub-assembly extends along the outer surface of the inversion support catheter; and
wherein the second inverting flexible tube sub-assembly includes a second flexible tube and a second puller coupled to the second flexible tube.

10. The method of claim 9 , wherein proximally retracting the first inverting flexible tube sub-assembly from the inversion support catheter includes pulling the first puller proximally so that the first flexible tube inverts over a distal end of the inversion support catheter.

11. The method of claim 9 , wherein the inversion support catheter is disposed within an intermediate catheter, and further comprising retracting the inversion support catheter from the intermediate catheter.

12. The method of claim 9 , wherein the second inverting flexible tube sub-assembly further comprises a cuff, and wherein loading the second inverting flexible tube sub-assembly onto the inversion support catheter includes sliding the cuff proximally along the inversion support catheter.

13. A thrombectomy catheter system, comprising:
an inversion support catheter;
a first tractor tube assembly coupled to the inversion support catheter, the first tractor tube assembly including a first knitted tractor tube and a first puller coupled to the first knitted tractor tube;
wherein the first tractor tube assembly is configured to be proximally retracted from the inversion support catheter;
wherein the first tractor tube assembly includes a cuff;
wherein the cuff is slidable along the inversion support catheter;
wherein the cuff is configured to split apart when the cuff reaches a distal end of the inversion support catheter;
a second tractor tube assembly, the second tractor tube assembly including a second knitted tractor tube and a second puller coupled to the second knitted tractor tube; and
wherein the second tractor tube assembly is configured to be reloaded onto the inversion support catheter, wherein the second tractor tube assembly is configured to be advanced through the distal end of the inversion support catheter and into the lumen, and a portion of the second tractor tube assembly inverts over the distal end of the inversion support catheter and extends along the outer surface of the inversion support catheter.

14. The thrombectomy catheter system of claim 13 , wherein the second tractor tube assembly includes a cuff.

15. The thrombectomy catheter system of claim 13 , wherein the first knitted tractor tube comprises a plurality of interlocking loops.

16. The thrombectomy catheter system of claim 13 , wherein the first knitted tractor tube is configured to be pulled proximally into the inversion support catheter by pulling the first puller proximally so that the first knitted tractor tube inverts over a distal end of the inversion support catheter.

Assignees

• Stryker Corp

Inventors

• Wallace Michael P
• Garabedian Robert
• Leguidleguid Roy
• Greenhalgh E Skott

Classifications

• A61M25/0119

  Eversible catheters · CPC title

• A61B2017/2215

  having an open distal end · CPC title

• A61B17/320725

  with radially expandable cutting or abrading elements (A61B17/32075 takes precedence) · CPC title

• A61B17/221 Primary

  Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)} · CPC title

• A61B2017/3435

  using everted sleeves · CPC title