Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US12287326B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12287326-B2 |
| Application number | US-202318299710-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 12, 2023 |
| Priority date | Aug 7, 2019 |
| Publication date | Apr 29, 2025 |
| Grant date | Apr 29, 2025 |
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Two rhodamine reversible fluorescent sensor derivatives, L 1 and L 2 , bearing 2-methoxy-1-naphthaldehyde and 5-bromo-3-methoxy salicylaldehyde units were synthesized using microwave-assisted organic synthesis and used for selective and sensitive reversible sequential fluorescence detection of aluminum ion (Al 3+ ) and azide (N 3− ) in aqueous acetonitrile solution via the fluorescence spectral changes. Stoichiometry and binding mechanisms for both sensors are well characterized and established by the respective spectroscopic techniques. L 1 and L 2 sensors are useful for the analysis of Al 3+ and N 3− in environmental samples and biological studies.
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The invention claimed is: 1. A compound having the formula: 2. A compound having the formula:
with only one oxygen atom as ring hetero atom in the oxygen-containing ring · CPC title
Nitrogen atoms · CPC title
without C-aluminium linkages · CPC title
producing a change of colour · CPC title
compounds with Al linked to an element other than Al, C, H or halogen (this includes Al-cyanide linkage) · CPC title
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