High flow oxygen therapy with on-demand humidification and an active exhalation valve

Patent metadata

Field	Value
Publication number	US-12285567-B2
Application number	US-201716468428-A
Country	US
Kind code	B2
Filing date	Dec 13, 2017
Priority date	Dec 14, 2016
Publication date	Apr 29, 2025
Grant date	Apr 29, 2025

Abstract

The present disclosure pertains to a system for delivering a humidified flow of concentrated oxygen containing gas to a subject, the system comprising: a subject interface; an oxygen concentrator operatively coupled to the subject interface, the oxygen concentrator configured to provide a flow of concentrated oxygen containing gas to the subject interface via a first conduit; and an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface via the second conduit to humidify the flow of concentrated oxygen containing gas for delivery to the subject.

First claim

What is claimed is:

1. A system for delivering a humidified flow of concentrated oxygen containing gas to a subject having a mouth and nares, the system comprising:
a subject interface structured to engage the mouth and/or nares of the subject;
an oxygen concentrator operatively coupled to the subject interface via a first control valve and a first conduit, the oxygen concentrator configured to provide a flow of concentrated oxygen containing gas to the subject interface via the first conduit;
a flow generator operatively coupled to the first conduit between the first control valve and the subject interface via a second control valve;
an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface to humidify the flow of concentrated oxygen containing gas at the subject interface;
an exhalation valve operatively coupled to the subject interface, the exhalation valve configured to control an expiratory pressure of gas expired by the subject;
one or more sensors configured to generate output signals that convey information related to one or more parameters of the concentrated oxygen containing gas; and
a controller configured to:
activate the aerosol generator responsive to the one or more parameters indicating a start of an inspiration, and de-activate the aerosol generator responsive to the one or more parameters indicating a start of an expiration;
control operations of the exhalation valve such that the exhalation valve is opened responsive to the one or more parameters indicating a start of an expiration, and the exhalation valve is closed responsive to the one or more parameters indicating a start of an inspiration; and
control operations of the first control valve to provide a controlled pressure and/or flow of breathable gas to the subject.

2. The system of claim 1 , wherein at least portions the first conduit and the second conduit are included in a multi-lumen tube.

3. The system of claim 2 , wherein the multi-lumen tube has an internal diameter of less than 8 millimeters.

4. The system of claim 1 , wherein the one more sensors are further configured to generate output signals that convey information related to humidity within the subject interface, and wherein the controller is further configured to control operations of the aerosol generator based on the humidity within the subject interface.

5. The system of claim 1 , wherein the controller is further configured to control operation of the second control valve to provide the controlled pressure and/or flow of the breathable gas to the subject.

6. The system of claim 1 , wherein the aerosol generator is provided as an integral part of the subject interface.

7. A method for delivering a humidified flow of concentrated oxygen containing gas to a subject having a mouth and nares, the method comprising:
providing, with an oxygen concentrator operatively coupled to a subject interface structured to engage the mouth and/or nares of the subject, a flow of concentrated oxygen containing gas to the subject interface via a first conduit;
providing, with an aerosol generator provided as an integral part of the subject interface and operatively coupled to a water supply via a second conduit, a water vapor to the subject interface to humidify the flow of concentrated oxygen containing gas at the subject interface;
controlling, with an exhalation valve operatively coupled to the subject interface, an expiratory pressure of gas expired by the subject;
controlling, with a first control valve positioned between the oxygen concentrator and the subject interface, the flow of concentrated oxygen containing gas to the subject interface;
generating, with one or more sensors, output signals that convey information related to one or more parameters of the concentrated oxygen containing gas;
activating, with a controller, the aerosol generator responsive to the one or more parameters indicating a start of an inspiration, and de-activate the aerosol generator responsive to the one or more parameters indicating a start of an expiration;
controlling, with the controller, operations of the exhalation valve such that the exhalation valve is opened responsive to the one or more parameters indicating a start of an expiration, and the exhalation valve is closed responsive to the one or more parameters indicating a start of an inspiration; and
controlling, with the controller, operations of the first control valve so as to provide a controlled pressure and/or flow of breathable gas to the subject.

8. The method of claim 7 , wherein the humidified flow of concentrated oxygen containing gas is delivered to the subject with a multi-lumen tube, and wherein at least portions of the first conduit and the second conduit are included in the multi-lumen tube.

9. The method of claim 7 , further comprising:
generating, with the one or more sensors, output signals that convey information related to humidity within the subject interface, wherein the controller is further configured to control operations of the aerosol generator based on the humidity within the subject interface.

10. The method of claim 7 , further comprising:
providing, with a flow generator operatively coupled to the first conduit between the first control valve and the subject interface, a flow of gas to the first conduit;
controlling, with a second control valve positioned between the flow generator and the first conduit, the flow of gas to the first conduit; and
controlling, with the controller, operations of the second control valve so as to provide the controlled pressure and/or flow of the breathable gas to the subject.

Assignees

• Koninklijke Philips Nv

Inventors

• Romano Robert

Classifications

• A61M2016/102

  Measuring a parameter of the content of the delivered gas · CPC title

• A61M16/205

  used for exhalation control · CPC title

• A61M16/101 Primary

  using an oxygen concentrator · CPC title

• A61M2230/40

  Respiratory characteristics · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title