Compositions and methods for targeted delivery to cells
US-2024390271-A1 · Nov 28, 2024 · US
US12280070B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12280070-B2 |
| Application number | US-202418955967-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 21, 2024 |
| Priority date | Jun 28, 2023 |
| Publication date | Apr 22, 2025 |
| Grant date | Apr 22, 2025 |
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A drug for the prevention or treatment of sepsis is provided. The drug comprises an exosome containing a circRNA MOTOR, and a nucleotide sequence corresponding to the circRNA MOTOR is shown in SEQ ID NO: 1.
Opening claim text (preview).
What is claimed is: 1. A drug for the prevention or treatment of sepsis, wherein the drug comprises an exosome containing a circRNA MOTOR, wherein a nucleotide sequence corresponding to the circRNA MOTOR is shown in SEQ ID NO: 1. 2. The drug of claim 1 , wherein a dosage form of the drug is at least one of a tablet, a capsule, an oral liquid, a lozenge, an aerosol, an injection, an ointment, or a granule. 3. The drug of claim 2 , wherein the dosage form of the drug is the injection.
Virus capsids or envelopes enclosing drugs (liposomes with additional exogenous lipids A61K9/127) · CPC title
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title
Antibacterial agents · CPC title
Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change · CPC title
Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells (presenting a specific antigen A61K39/00; therapeutic combinations of antibodies, or fragments thereof, and blood-derived cells A61K39/00) · CPC title
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