Templated open flocs of anisotropic particles for enhanced pulmonary delivery

US12263243B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12263243-B2
Application numberUS-37157309-A
CountryUS
Kind codeB2
Filing dateFeb 13, 2009
Priority dateFeb 13, 2008
Publication dateApr 1, 2025
Grant dateApr 1, 2025

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Abstract

Official abstract text for this publication.

The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.

First claim

Opening claim text (preview).

What is claimed is: 1. Flocculated pharmaceutically active starting drug particles (“starting floc drug particles”), of one or more drugs, the starting floc drug particles having aerodynamic diameters that have not been pre-formed, the starting floc drug particles being positioned in a dry powder inhaler (dpi) having one or more particle exit orifices, the starting floc drug particles being anisotropic and asymmetric such that when the dpi is actuated, the starting floc drug partic…

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What does patent US12263243B2 cover?
The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane d…
Who is the assignee on this patent?
Johnston Keith P, Engstrom Joshua, Tam Jasmine, and 3 more
What technology area does this patent fall under?
Primary CPC classification A61K9/008. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Apr 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).