Tool for the communication of treatment option risks and benefits

Patent metadata

Field	Value
Publication number	US-12260941-B2
Application number	US-202217885054-A
Country	US
Kind code	B2
Filing date	Aug 10, 2022
Priority date	Aug 10, 2022
Publication date	Mar 25, 2025
Grant date	Mar 25, 2025

Abstract

A tool for assessing treatment options within a risk-benefit space (plotting risk against benefit) and provides a superimposed boundary indicating patient risk-benefit preference for assessment of these options. The patient risk-benefit preference can be used to identify a preferred treatment option, and interactive controls can be provided to change risk-benefit preference, risk categories, benefit categories, disease type, and the like.

First claim

What we claim is:

1. A tool for visualizing the risks and benefits of multiple medical treatment options and comprising:
a processor providing an electronic database of risks and benefits of different treatment options and executing program instructions stored in a computer-readable storage medium and providing a display to:
(a) receive information for a given patient characterizing a risk-benefit preference by the patient with respect to medical treatment;
(b) access the database to provide a display of a set of multiple treatment option markers associated with different medical treatment options and arranged in a display area along a first axis according to treatment option benefit and along a second axis according to treatment option risk; and
(c) use the received information to interactively superimpose on the display area an iso-preference boundary of equal risk-benefit preferences by the patient.

2. The tool of claim 1 wherein the iso-preference boundary intersects at least one marker indicating a treatment option.

3. The tool of claim 2 wherein the iso-preference boundary is an iso-preference boundary intersecting at least one marker.

4. The tool of claim 2 wherein the iso-preference boundary is represented by a band having at least one of a risk-extent and benefit-extent of at least 5%.

5. The tool of claim 1 wherein the processor further executes to highlight markers on the iso-preference boundary and/or on a side of the iso-preference boundary of having lower-cost function values, the cost function relating risks and benefits of a treatment option weighted according to patient risk-benefit preference.

6. The tool of claim 1 wherein the markers provide varying areas in the display area according to empirical uncertainty in the probability of risk and benefit of a treatment option represented by the marker with treatment options associated with larger uncertainty having larger areas.

7. The tool of claim 1 wherein the first and second axes have a range of 0 to 100%.

8. The tool of claim 1 wherein the processor further accepts an input selection of categories of benefits and uses the input selection of categories to locate the markers and the iso-preference boundary along the first axis of the display area.

9. The tool of claim 8 wherein the categories are selected from the group consisting of: survival fraction at a selected time cutoff, objective response rate, and clinical benefit rate.

10. The tool of claim 1 wherein the processor further accepts inputs of categories risks and uses the input selection of categories to locate the markers and the iso-preference boundary along the second axis of the display area.

11. The tool of claim 10 wherein categories are selected from the group consisting of: any adverse medical event, any adverse medical events over a predetermined grade threshold, and any subset of specific organ toxicities.

12. The tool of claim 1 wherein categories are selected from the group consisting of: direct cost to the patient and inconvenience or indirect cost to the patient.

13. The tool of claim 1 wherein the information for a given patient characterizing the risk-benefit preference by the patient is entered by an interactive control manipulable by a patient.

14. The tool of claim 1 wherein the processor receives patient-specific clinical information for a given patient and the treatment option risks or benefits for the treatment options may be based on the patient-specific clinical information.

15. The tool of claim 1 further providing a display of a multiple markers associated with a given medical treatment option over different times during a patient treatment with the given medical treatment option indicating a change in the risk-benefit of the given medical procedure informed by analysis of patient-specific data with respect to a given patient.

16. The tool of claim 15 wherein the processor further accepts inputs of medical procedure categories and provides a display of a set of multiple treatment options according to an input of a medical procedure category.

17. The tool of claim 1 wherein the processor receives a user-selectable maximum risk level and a minimum benefit level and wherein the display area displays markers only associated with treatment option benefits above the minimum benefit level and treatment option risks below the maximum risk level.

Assignees

• Wisconsin Alumni Res Found

Inventors

• Jeraj Robert
• Huff Daniel Tyler

Classifications

• G06F3/04842

  Selection of displayed objects or displayed text elements (G06F3/0482 takes precedence) · CPC title

• G16H50/30

  for calculating health indices; for individual health risk assessment · CPC title

• G16H20/00 Primary

  ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance · CPC title

• G06F3/04847 Primary

  Interaction techniques to control parameter settings, e.g. interaction with sliders or dials · CPC title