Delivery of therapeutic neuromodulation
US-2021068793-A1 · Mar 11, 2021 · US
US12257458B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12257458-B2 |
| Application number | US-202318325982-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 30, 2023 |
| Priority date | Dec 10, 2020 |
| Publication date | Mar 25, 2025 |
| Grant date | Mar 25, 2025 |
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The present application provides an ultrasonic wake-up system. The system includes an ultrasonic imaging device, an ultrasound stimulation device, and an ultrasound stimulation effect evaluation device, and acquires an ultrasonic image of a target object through the ultrasonic imaging device, transmits an ultrasound to the target object based on the ultrasonic image through the ultrasound stimulation device, and adjusts the transmitted ultrasound required through the ultrasound stimulation effect evaluation device. Therefore, peripheral nerves are accurately stimulated, an uplink reticular wake-up system is activated, so as to wake up patients with disorders of consciousness.
Opening claim text (preview).
What is claimed is: 1. An ultrasonic wake-up system, comprising: an ultrasonic imaging device, an ultrasound stimulation device, and an ultrasound stimulation effect evaluation device; wherein the ultrasonic imaging device, the ultrasound stimulation device, and the ultrasound stimulation effect evaluation device are connected with each other; the ultrasonic imaging device is configured for acquiring an ultrasonic image of a target object; the ultrasound stimulation device is configured for transmitting an ultrasound to the target object based on the ultrasonic image; and the ultrasound stimulation effect evaluation device is configured for detecting a physiological signal of the target object and adjusting the ultrasound based on the physiological signal; wherein the ultrasound stimulation device comprises an ultrasonic parameter selecting unit, an ultrasonic transmitting processing unit and an ultrasonic transducer unit, the ultrasonic parameter selecting unit is configured for determining an ultrasonic parameter corresponding to the target object, and the ultrasonic parameter is configured for determining a frequency domain characteristic and a time domain characteristic of the ultrasound transmitted to the target object; wherein the ultrasonic transmitting processing unit is configured for determining a depth of a target area for transmitting the ultrasound to the target object according to the ultrasonic image, determining a deployment location of the ultrasonic transducer unit based on the depth of the target area, and controlling the ultrasonic transducer unit to transmit the ultrasound based on the depth of the target area and the ultrasonic parameter; and wherein the ultrasound stimulation effect evaluation device is configured for adjusting the depth of the target area and the ultrasonic parameter based on the physiological signal, and the physiological signal comprises at least one of an electromyographic signal, an electroencephalographic signal, and a behavioral data rating. 2. The system according to claim 1 , wherein the ultrasonic parameter selecting unit is specifically configured for: determining the ultrasonic parameter based on a physiological characteristic of the target object and/or the target area information. 3. The system according to claim 1 , wherein the ultrasonic transducer unit comprises: at least one ultrasonic transducer, the ultrasonic transducer comprising at least one ultrasonic array element; the ultrasonic transmitting processing unit is connected with the at least one ultrasonic transducer; and the ultrasonic transducer is configured for receiving a first control instruction output by the ultrasonic transmitting processing unit, and controlling at least one ultrasonic array element to send the ultrasound based on the first control instruction. 4. The system according to claim 1 , wherein the ultrasonic parameter comprises: at least one of ultrasonic frequency, ultrasonic duration, ultrasonic intensity, pulse repetition frequency, and duty cycle. 5. The system according to claim 1 , wherein the ultrasound stimulation effect evaluation device is further configured for: detecting a basic physiological index of the target object, wherein the basic physiological index comprises: at least one of heart rate, body temperature, and respiration; evaluating safety of the ultrasound based on the basic physiological index; and when an evaluation result indicates that the safety of the ultrasound is lower than a preset value, sending a second control instruction to the ultrasound stimulation device, wherein the second control instruction is configured for instructing the ultrasound stimulation device to stop transmitting the ultrasound or adjusting the ultrasonic parameter.
for diagnosis of the brain · CPC title
for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules · CPC title
Stimulation of nerve tissue · CPC title
Control of the diagnostic device · CPC title
involving processing of raw data to produce diagnostic data, e.g. for generating an image · CPC title
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