Devices, systems, and methods for treatment of intracranial aneurysms

Patent metadata

Field	Value
Publication number	US-12256936-B2
Application number	US-202318324017-A
Country	US
Kind code	B2
Filing date	May 25, 2023
Priority date	Nov 4, 2019
Publication date	Mar 25, 2025
Grant date	Mar 25, 2025

Abstract

Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity and deforming a shape of the occlusive member via introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall.

First claim

We claim:

1. An aneurysm occlusion device, comprising:
a mesh comprising inner and outer layers and configured to compress for delivery through a catheter and expand upon release from the constraint of the catheter into an expanded configuration for positioning within an aneurysm, wherein the inner and outer layers meet distally at a fold and proximally at a hub, and
wherein, in the expanded configuration and when positioned within the aneurysm, the mesh comprises a proximal region configured to be disposed over a neck of the aneurysm, a distal region configured to be within the aneurysm cavity, and a lateral region between the proximal and distal regions that is configured to press outwardly on the aneurysm wall, wherein the lateral region comprises a portion of a central region of the aneurysm occlusion device, and
wherein the inner and outer layers contact one another along the proximal and lateral regions of the mesh, and
wherein the inner and outer layers conform to one another along the proximal and lateral regions and have different shapes along the distal region.

2. The device of claim 1 , wherein, along the distal region, along the distal region, the inner and outer layers are spaced apart from one another along a height dimension of the mesh by a distance, and wherein the distance increases as the layers extend radially inwardly.

3. The device of claim 1 , wherein the inner layer has a first portion that curves distally and radially away from the hub and a second portion that extends away from the first portion and radially inwardly, and wherein the inner layer is generally straight along the second portion.

4. The device of claim 1 , wherein a radially inner surface of the inner layer defines a cavity.

5. The device of claim 1 , wherein, at the distal region of the mesh, the inner and outer layers define a cavity.

6. The device of claim 1 , wherein:
the inner layer defines a first cavity,
at the distal region of the mesh, the inner and outer layers define a second cavity,
wherein the second cavity is distal of the first cavity.

7. The device of claim 1 , wherein the mesh comprises a plurality of braided filaments.

8. The device of claim 1 , wherein the fold surrounds an opening.

9. The device of claim 1 , wherein the fold is radially inward of a maximum diameter of the mesh.

10. An aneurysm occlusion device, comprising:
a mesh comprising inner and outer layers and configured to compress for delivery through a catheter and expand upon release from the constraint of the catheter into an expanded configuration, wherein the inner and outer layers meet distally at a fold and proximally at a hub, and
wherein, in the expanded configuration and when positioned within an aneurysm, the mesh comprises a proximal region configured to be disposed over a neck of the aneurysm, a distal region configured to be within the aneurysm cavity, and a lateral region between the proximal and distal regions that is configured to press outwardly on the aneurysm wall, and wherein the mesh has a height measured between the hub and a distalmost surface of the mesh,
wherein the outer layer of the mesh extends continuously in a radially inward direction along the distal region,
wherein a distance between the inner and outer layers is greater along the distal region than it is along the proximal and lateral regions, and
wherein the inner and outer layers contact one another continuously along the proximal and lateral regions of the mesh.

11. The device of claim 10 , wherein a distance between the inner and outer layers along a height dimension of the mesh increases as the layers extend radially inwardly.

12. The device of claim 10 , wherein the inner layer has a first portion that curves distally and radially away from the hub and a second portion that extends from the first portion and radially inwardly, and wherein the inner layer is generally straight along the second portion.

13. The device of claim 10 , wherein a radially inner surface of the inner layer defines a cavity.

14. The device of claim 10 , wherein, at the distal region of the mesh, the inner and outer layers define a cavity.

15. The device of claim 10 , wherein:
the inner layer defines a first cavity,
at the distal region of the mesh, the inner and outer layers define a second cavity,
wherein the second cavity is distal of the first cavity.

16. The device of claim 10 , wherein the mesh comprises a plurality of braided filaments.

17. The device of claim 10 , wherein the fold surrounds an opening.

18. The device of claim 10 , wherein the fold is radially inward of a maximum diameter of the mesh.

Assignees

• Covidien Lp

Inventors

• Li Junwei
• Wainwright John
• Girdhar Gaurav
• Sosnowski Stephen

Classifications

• A61B2090/3966

  Radiopaque markers visible in an X-ray image · CPC title

• A61B2090/376

  using X-rays, e.g. fluoroscopy · CPC title

• A61B17/12145

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title

• A61B2017/00862

  elastic or resilient · CPC title

• A61B2017/00557

  inflatable (A61B2017/22051 takes precedence) · CPC title