Configuration for ultra high pressure electrolytic eluent generators

Patent metadata

Field	Value
Publication number	US-12247307-B2
Application number	US-202117565643-A
Country	US
Kind code	B2
Filing date	Dec 30, 2021
Priority date	Dec 30, 2021
Publication date	Mar 11, 2025
Grant date	Mar 11, 2025

Abstract

An electrolytic eluent generator includes an electrolyte reservoir and at least one eluent generation cartridge. The electrolyte reservoir includes a chamber containing an aqueous electrolyte solution; and a first electrode. The at least one eluent generation cartridge includes a platinum mesh electrode; a polymer screen; a plurality of reinforced membranes; a membrane washer; and a spacer including a central post and an annular projection.

First claim

What is claimed is:

1. An eluent generation cartridge comprising:
a platinum mesh electrode;
a polymer screen;
a plurality of reinforced membranes;
a membrane washer including at least one ion exchange membrane; and
a spacer including a central post and an annular projection,
wherein the membrane washer is deformable into an annular space between the annular projection and the central post during compression such that a gap is formed between the membrane washer and the adjacent ion exchange membrane.

2. The eluent generation cartridge of claim 1 wherein the eluent generation cartridge is configured to operate at a pressure of at least about 5,000 psi.

3. The eluent generation cartridge of claim 2 wherein the eluent generation cartridge is configured to operate at a pressure of at least about 10,000 psi.

4. The eluent generation cartridge of claim 2 wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 30,000 psi.

5. The eluent generation cartridge of claim 4 wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 15,000 psi.

6. The eluent generation cartridge of claim 1 wherein the plurality of reinforced membranes includes at least 5 ion exchange membranes.

7. The eluent generation cartridge of claim 6 wherein the plurality of reinforced membranes includes not more than about 100 ion exchange membranes.

8. The eluent generation cartridge of claim 1 wherein the membrane washer includes not more than about 20 ion exchange membranes.

9. An electrolytic eluent generator comprising:
an electrolyte reservoir including:
a chamber containing an aqueous electrolyte solution; and
a first electrode:

at least one eluent generation cartridge including:
a platinum mesh electrode;
a polymer screen:
a plurality of reinforced membranes;
a membrane washer including at least one ion exchange membrane; and
a spacer including a central post and an annular projection,
wherein the membrane washer is deformable into an annular space between the annular projection and the central post during compression such that a gap is formed between the membrane washer and the adjacent ion exchange membrane.

10. The electrolytic eluent generator of claim 9 wherein the eluent generation cartridge is configured to operate at a pressure of at least about 5,000 psi.

11. The electrolytic eluent generator of claim 10 wherein the eluent generation cartridge is configured to operate at a pressure of at least about 10,000 psi.

12. The electrolytic eluent generator of claim 10 wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 30,000 psi.

13. The electrolytic eluent generator of claim 12 wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 15,000 psi.

14. The electrolytic eluent generator of claim 9 wherein the aqueous electrolyte solution includes potassium hydroxide or sodium hydroxide.

15. The electrolytic eluent generator of claim 9 wherein the aqueous electrolyte solution includes methanesulfonic acid.

16. The electrolytic eluent generator of claim 9 wherein the plurality of reinforced membranes includes at least 5 ion exchange membranes.

17. The electrolytic eluent generator of claim 16 wherein the plurality of reinforced membranes includes not more than about 100 ion exchange membranes.

18. The electrolytic eluent generator of claim 9 wherein the membrane washer includes not more than about 20 ion exchange membranes.

Assignees

• Dionex Corp

Inventors

• Lu Zhongqing
• Liu Yan
• Rubero Jr Angelo
• Lin Rong

Classifications

• C25B1/16

  Hydroxides (by simultaneous production of alkali metal hydroxides and chlorine, oxyacids or salts of chlorine C25B1/34) · CPC title

• G01N2030/965

  suppressor columns · CPC title

• G01N30/96 Primary

  using ion-exchange (G01N30/02, G01N30/90 take precedence) · CPC title

• C25B13/02

  characterised by shape or form · CPC title

• B01D15/426

  Specific type of solvent · CPC title