Injection device

Patent metadata

Field	Value
Publication number	US-12233247-B2
Application number	US-202318449981-A
Country	US
Kind code	B2
Filing date	Aug 15, 2023
Priority date	Nov 7, 2017
Publication date	Feb 25, 2025
Grant date	Feb 25, 2025

Abstract

An injection device includes an elongated housing extending along a longitudinal axis, a piston rod to operably engage with a piston of a cartridge filled with the medicament, a dose tracker selectively operably engageable with the piston rod, wherein the dose tracker is longitudinally displaceable relative to the housing from an initial position in a proximal direction towards at least a first activation position for setting of the dose and wherein the dose tracker is longitudinally displaceable relative to the housing in a distal direction from the at least first activation position towards the initial position for dispensing of the dose, a spring to urge the dose tracker in the proximal direction relative to the housing, an interlock to lock the dose tracker in the initial position relative to the housing, and a release member to release the interlock.

First claim

The invention claimed is:

1. An injection device for setting and injecting a dose of a medicament, the injection device comprising:
an elongated housing extending along a longitudinal axis;
a piston rod to operably engage with a piston of a cartridge filled with the medicament;
a dose tracker selectively operably engageable with the piston rod, wherein the dose tracker is longitudinally displaceable relative to the housing from an initial position in a proximal direction towards a first activation position during setting of the dose and wherein the dose tracker is longitudinally displaceable relative to the housing in a distal direction from the first activation position towards the initial position during dispensing of the dose;
a spring to urge the dose tracker in the proximal direction relative to the housing;
an interlock to lock the dose tracker in the initial position relative to the housing;
a release member to release the interlock;
at least one first tracking stop feature provided on one of the dose tracker and the housing, wherein the at least one first tracking stop feature is configured to block a longitudinal displacement of the dose tracker relative to the housing when the dose tracker reaches the first activation position; and
a preselector separate from the release member and comprising at least one first preselector stop feature to engage with the at least one first tracking stop feature, wherein the preselector is at least one of translationally and rotationally displaceable relative to the housing between at least two preselection positional states.

2. The injection device according to claim 1 , wherein the preselector is lockable to at least one of the housing and the dose tracker in any of the at least two preselection positional states.

3. The injection device according to claim 1 , wherein the preselector is rotationally supported on or in at least one of the housing and the dose tracker,
a) wherein the preselector comprises at least one second preselector stop feature being at least one of tangentially and longitudinally offset from the at least one first preselector stop feature, or
b) wherein at least one of the dose tracker and the housing comprises at least one second tracking stop feature being at least one of tangentially and longitudinally offset from the at least one first tracking stop feature.

4. The injection device according to claim 3 , wherein the at least one first preselector stop feature comprises a first stop face configured to abut with a second stop face of the at least one first tracking stop feature.

5. The injection device according to claim 4 , wherein the at least one second preselector stop feature comprises a third stop face longitudinally offset from the first stop face of the at least one first preselector stop feature.

6. The injection device according to claim 1 , wherein one of the at least one first tracking stop feature and the at least one first preselector stop feature comprises a first radial protrusion and wherein the other one of the at least one first tracking stop feature and the at least one first preselector stop feature comprises at least one of
a) a second radial protrusion configured to abut with the first radial protrusion; and
b) a groove configured to slidably receive the first radial protrusion.

7. The injection device according to claim 1 , further comprising a trigger integrally formed or longitudinally engaged with the dose tracker, wherein at least one of the trigger and a proximal end of the dose tracker protrudes from a proximal end of the housing when the dose tracker is in the first activation position.

8. The injection device according to claim 7 , wherein a longitudinal distance between the initial position and the first activation position of the dose tracker correlates with the size of the dose.

9. The injection device according to claim 1 , wherein the spring has a first end operably connected to the housing and has a second end operably connected to the dose tracker, wherein the spring comprises a cylindrically shaped compression spring or a helically wound torsion spring, and wherein the spring encloses at least a portion of the dose tracker or wherein the spring is arranged inside a hollow portion of the dose tracker.

10. The injection device according to claim 1 , wherein the release member comprises an annular ring rotationally supported at a proximal end of the housing, wherein one of an inside surface of the annular ring and an outside surface of the dose tracker comprises at least one catch element to engage with a protrusion on the other one of the inside surface of the annular ring and the outside surface of the dose tracker.

11. The injection device according to claim 1 , wherein the release member comprises a release button located in a recess of a sidewall of the housing and depressible into the housing for releasing the dose tracker.

12. The injection device according to claim 1 , wherein the interlock comprises a first engaging structure connected to or integral with the dose tracker and a second engaging structure connected to or integral with the release member and wherein the first engaging structure and the second engaging structure are positively engaged with regard to the longitudinal direction when the at least one release member is in an initial position and when the dose tracker is in the initial position, wherein the first and the second engaging structures are disengaged when the at least first one release member is depressed.

13. The injection device according to claim 1 , further comprising the cartridge comprising a barrel filled with the medicament and sealed by the piston that is axially displaceable relative to the barrel by the piston rod.

14. The injection device according to claim 1 , wherein preselected doses of different sizes of the medicament can be defined by moving the preselector relative to the housing.

15. The injection device according to claim 1 , wherein the preselector is fixed or locked to the housing during setting of the dose and during dispensing of the dose of the medicament.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Helmer Michael
• Schabbach Michael
• Kersting Julian

Classifications

• A61M5/31585

  performed by axially moving actuator, e.g. an injection button · CPC title

• A61M5/31563

  interacting with a displaceable stop member · CPC title

• A61M5/3156

  using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals · CPC title

• A61M5/31575

  using scaling up or down transmissions, e.g. gearbox · CPC title

• A61M5/24

  Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic {(ampoules or carpules A61J1/06)} · CPC title