Nitric oxide releasing high density lipoprotein-like nanoparticles (no hdl nps)
US-2020281962-A1 · Sep 10, 2020 · US
US12220394B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12220394-B2 |
| Application number | US-201916972898-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 6, 2019 |
| Priority date | Jun 7, 2018 |
| Publication date | Feb 11, 2025 |
| Grant date | Feb 11, 2025 |
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The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, a kidney inflammation inhibitor, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-alanine or a derivative thereof. In addition, the present invention pertains to the use of D-alanine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.
Opening claim text (preview).
The invention claimed is: 1. A method for treatment of kidney disease, comprising: administrating D-alanine to a subject in need thereof, wherein the kidney disease is chronic kidney disease, ischemia-induced kidney disorder, or inflammation-induced kidney disorder. 2. The method according to claim 1 , wherein the D-alanine is used for kidney protection or restoration of kidney function. 3. The method according to claim 1 , wherein the administration is local administration, enteral administration or parenteral administration. 4. The method according to claim 1 , wherein the kidney disease is chronic kidney disease. 5. The method according to claim 1 , wherein the kidney disease is ischemia-induced kidney disorder. 6. The method according to claim 1 , wherein the kidney disease is inflammation-induced kidney disorder.
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