Hemostat reconstitution methods and devices
US-2023165944-A1 · Jun 1, 2023 · US
US12208176B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12208176-B2 |
| Application number | US-202117221959-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 5, 2021 |
| Priority date | Jun 1, 2010 |
| Publication date | Jan 28, 2025 |
| Grant date | Jan 28, 2025 |
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Official abstract text for this publication.
Described is a process for making a dry and stable hemostatic composition, said process comprising a) providing a first component comprising a dry preparation of a coagulation inducing agent, b) providing a second component comprising a dry preparation of a biocompatible polymer suitable for use in hemostasis, c) providing said first component and said second component in a combined form in a final container, c1) either by filling said first component and said second component into said final container so as to obtain a dry mixture in said final container, c2) or by providing said first component or said second component in said final container and adding said second component or said first component so as to obtain a combination of said first component with said second component in said final container, d) finishing the final container to a storable pharmaceutical device containing said first component and said second component in a combined form as a dry and stable hemostatic composition.
Opening claim text (preview).
The invention claimed is: 1. A sterile storage stable pharmaceutical product consisting of: a sterile syringe containing a sterile dry mixture of a dry thrombin preparation and dry cross-linked gelatin granules, the pharmaceutical product being solid state, sterilized and sealed. 2. The pharmaceutical product of claim 1 , wherein the dry thrombin preparation is a dry particulate thrombin preparation. 3. The pharmaceutical product of claim 1 , wherein the dry thrombin preparation is a dry thrombin powder. 4. The pharmaceutical product of claim 1 , wherein the thrombin preparation comprises human thrombin. 5. The pharmaceutical product of claim 1 , wherein the dry thrombin preparation is recombinant human thrombin.
Thrombin (3.4.21.5) · CPC title
Sterilising, e.g. of complete packages · CPC title
Introducing successive articles, e.g. confectionery products, of different shape or size in predetermined positions · CPC title
Filling medical containers such as ampoules, vials, syringes or the like · CPC title
Flowable or injectable implant compositions · CPC title
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