System and methods for laser-assisted nanotexturing and silver immobilization on titanium implant surfaces

Patent metadata

Field	Value
Publication number	US-12208012-B2
Application number	US-202218092267-A
Country	US
Kind code	B2
Filing date	Dec 31, 2022
Priority date	Feb 25, 2022
Publication date	Jan 28, 2025
Grant date	Jan 28, 2025

Abstract

A method for manufacturing an implantable device is provided. The method includes laser nano-texturing a titanium surface. The method further includes applying an aqueous silver ion solution to form a silver ion complex on the nano-textured titanium surface. The method also includes reducing, using laser-assisted photocatalytic reduction, the silver ion complex to silver ion particles which are immobilized on the nano-textured titanium surface.

First claim

The invention claimed is:

1. A method, comprising:
laser nano-texturing a titanium surface of a device configured to be at least partially implanted into a living subject;
applying an aqueous silver ion solution to form a silver ion complex on the nano-textured titanium surface; and
reducing, using laser-assisted photocatalytic reduction, the silver ion complex to silver ion particles which are immobilized on the nano-textured titanium surface.

2. The method of claim 1 , wherein laser nano-texturing the titanium surface further comprises:
directing a laser at the surface and forming hierarchical porous structures on the titanium surface.

3. The method of claim 1 , wherein reducing, using laser-assisted photocatalytic reduction, the silver ion complex to silver ion particles immobilized on the nano-texturing surface further comprises:
directing a laser at the silver ion complexes on the nano-textured titanium surface to form the immobilized silver ion particles.

4. The method of claim 1 , where in the laser nanotexturing occurs is performed at a first power and the laser-assisted photocatalytic reduction is performed at a second power, wherein the first power is greater than the second power.

5. The method of claim 4 , wherein the laser nanotexturing and the reducing is performed with a same laser.

6. The method of claim 1 , wherein the silver ion complex comprises [Ag(NH 3 ) 2 ] + .

7. The method of claim 1 , wherein the device is an orthopedic device and the surface is configured to receive or adjoin a bone.

Assignees

• Purdue Research Foundation

Inventors

• Rahimi Rahim
• Selvamani Vidhya

Classifications

• A61F2002/3084

  Nanostructures · CPC title

• A61F2002/30784

  Plurality of holes · CPC title

• A61F2002/3097

  using laser · CPC title

• A61F2310/00023

  Titanium or titanium-based alloys, e.g. Ti-Ni alloys · CPC title

• A61F2310/0052

  Coating made of silver or Ag-based alloys · CPC title