Compounds that modulate fatty acid receptor activity and pet food products containing the same

Patent metadata

Field	Value
Publication number	US-12207673-B2
Application number	US-202017013919-A
Country	US
Kind code	B2
Filing date	Sep 8, 2020
Priority date	Dec 10, 2014
Publication date	Jan 28, 2025
Grant date	Jan 28, 2025

Abstract

A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.

First claim

We claim:

1. A flavor composition comprising a compound of Formula III comprising the structure

wherein
X is O, S, C(O), or a chemical bond;
X 1 is O or S;
Y is COOH, SO 3 H, —OP(O)(OH) 2 , or tetrazole;
W is halogen, COOH, COOMe, CN, CHO, aryl, OH, H, —S-aryl, —O-aryl, —N-aryl, CF 3 , OCH 3 , CH 3 , NO 2 , or OEt;
R is CH 3 ;
n 1 is 0-4;
n 2 is 0-2; and
n 3 is 1-12 or branched or unbranched C 2 -C 20
wherein the compound is present in the flavor composition at a concentration of from about 0.001 μM to about 1 mM and wherein the compound is a GPR120 agonist.

2. The flavor composition of claim 1 , wherein the compound is 4-[4-(heptyloxy)phenyl]-4-oxobutanoic acid.

3. A food product comprising the flavor composition of claim 1 , wherein the flavor composition is present in an amount effective to increase a fatty acid taste or the palatability of the food product as determined by a panel of taste testers.

4. The food product of claim 3 , wherein the flavor composition is present at a concentration of from about 10 pM to about 1 M, from about 0.01 ppm to 1,000 ppm, or from about 0.01% to about 10% w/w in the food product.

5. The food product of claim 3 , wherein the food product comprises a pet food product.

6. The food product of claim 5 , wherein the pet food product is a feline pet food product or a canine pet food product.

7. The food product of claim 6 , wherein the pet food product is a wet pet food product.

8. The food product of claim 6 , wherein the pet food product is a dry pet food product.

9. A method of increasing a fatty acid taste intensity in a food product comprising admixing a food product with the flavor composition of claim 1 , wherein the flavor composition is present in an amount effective to increase a fatty acid taste of the food product as determined by a panel of taste testers.

10. The method of claim 9 , wherein the flavor composition is present at a concentration of from about 10 pM to about 1 M, of from about 0.01 ppm to 1,000 ppm, or from about 0.01% to about 10% w/w in the admixture.

Assignees

• Mars Inc

Inventors

• Mcgrane Scott Joseph
• Gibbs Matthew Ronald
• Fine Richard Masten
• Skiles Jerry Wallace

Classifications

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A23L27/235

  containing also amino acids · CPC title

• A23L27/22

  containing glutamic acids · CPC title

• A23L27/21

  containing amino acids · CPC title

• A23K20/142

  Amino acids; Derivatives thereof · CPC title