Method for pretreatment and method for analysis of lenalidomide in biological sample
US-2017192024-A1 · Jul 6, 2017 · US
Method of testing a blood for macrolide immunosuppressant
US12196768B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12196768-B2 |
| Application number | US-201816957301-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 19, 2018 |
| Priority date | Dec 25, 2017 |
| Publication date | Jan 14, 2025 |
| Grant date | Jan 14, 2025 |
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- Title
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Abstract
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The present invention provides a method of testing a blood for a macrolide immunosuppressant conveniently and/or highly accurately. Specifically, the present invention provides a method of testing a blood for a macrolide immunosuppressant, including: (a) treating a blood sample containing a macrolide immunosuppressant or a metabolite thereof having a macrolide structure with an acid or an alkali; and (b) measuring a concentration of the macrolide immunosuppressant or the metabolite in the blood sample by using an antibody.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of testing a blood for a macrolide immunosuppressant that is tacrolimus, the method comprising: (a) treating a blood sample comprising tacrolimus with an acidic buffer having a pH in a range of 2.0 to 4.5 to form an acidic blood sample containing the tacrolimus, and wherein the acidic blood sample containing the tacrolimus does not contain a volatile organic solvent; and (b) measuring a concentration of the tacrolimus in the acidic blood sample by contacting the acidic blood sample with an antibody that specifically binds to the tacrolimus, and the antibody is IgG, IgM, or an antibody fragment thereof, and immobilized to a solid phase. 2. The method of claim 1 , wherein the blood sample is a human blood sample.
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Classifications
- G01N33/5308Primary
for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites · CPC title
- G01N33/9493Primary
Immunosupressants · CPC title
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- What does patent US12196768B2 cover?
- The present invention provides a method of testing a blood for a macrolide immunosuppressant conveniently and/or highly accurately. Specifically, the present invention provides a method of testing a blood for a macrolide immunosuppressant, including: (a) treating a blood sample containing a macrolide immunosuppressant or a metabolite thereof having a macrolide structure with an acid or…
- Who is the assignee on this patent?
- Fujirebio Kk
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5308. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Jan 14 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).