Biological hair shape change composition and kit, and method for changing hair shape

Patent metadata

Field	Value
Publication number	US-12194137-B2
Application number	US-202117513484-A
Country	US
Kind code	B2
Filing date	Oct 28, 2021
Priority date	Jul 16, 2021
Publication date	Jan 14, 2025
Grant date	Jan 14, 2025

Abstract

A biological hair shape change composition including a macromolecular component, a small molecular component and an alkali agent component is provided. The macromolecular component includes a protease belonging to the class of alkaline proteases, and the small molecular component includes a peptide with reduction activity. Both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium. Molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

First claim

What is claimed is:

1. A biological hair shape change composition, comprising:
a macromolecular component, comprising:
a protease belonging to the class of alkaline proteases;
a small molecular component, comprising:
a peptide with reduction activity; and
an alkali agent component,
wherein both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium, and
wherein molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

2. The biological hair shape change composition as claimed in claim 1 , wherein the protease belonging to the class of alkaline proteases comprises alkaline protease, keratinase or a combination thereof.

3. The biological hair shape change composition as claimed in claim 1 , wherein an activity of the protease belonging to the class of alkaline proteases is 150-3000 U/mL.

4. The biological hair shape change composition as claimed in claim 1 , wherein the length of the peptide with reduction activity is 5-30 amino acids.

5. The biological hair shape change composition as claimed in claim 1 , wherein the peptide with reduction activity comprises at least one of the following peptides:
(a) a peptide comprising the amino acid sequence of SEQ ID NO. 1;
(b) a peptide comprising the amino acid sequence of SEQ ID NO. 2;
(c) a peptide comprising the amino acid sequence of SEQ ID NO. 3;
(d) a peptide comprising the amino acid sequence of SEQ ID NO. 4;
(e) a peptide comprising the amino acid sequence of SEQ ID NO. 5;
(f) a peptide comprising the amino acid sequence of SEQ ID NO. 6;
(g) a peptide comprising the amino acid sequence of SEQ ID NO. 7;
(h) a peptide comprising the amino acid sequence of SEQ ID NO. 8;
(i) a peptide comprising the amino acid sequence of SEQ ID NO. 9; and
(j) a peptide comprising the amino acid sequence of SEQ ID NO. 10.

6. The biological hair shape change composition as claimed in claim 1 , wherein the alkali agent component comprises a plant-derived alkali agent and/or a chemical synthesis-derived alkali agent.

7. The biological hair shape change composition as claimed in claim 6 , wherein the plant-derived alkali agent comprises at least one of the following plant-derived alkali extracts:
a water extract of coffee grounds, a water extract of tea stems, and a water extract of mulberry leaves.

8. The biological hair shape change composition as claimed in claim 1 , wherein a concentration of the alkali agent component in the biological hair shape change composition is 1-80% (v/v).

9. The biological hair shape change composition as claimed in claim 1 , wherein the Bacillus licheniformis comprises Bacillus licheniformis BCRC 14353, Bacillus licheniformis GI_5E-1 of which the deposit number is CCTCC M 20211045, or a combination thereof.

10. The biological hair shape change composition as claimed in claim 1 , wherein the keratin and/or keratin polymer-containing medium comprise a keratin and/or keratin polymer-containing substance, and the keratin and/or keratin polymer-containing substance comprises feathers, hair, hooves, claws and/or horns of animals.

11. The biological hair shape change composition as claimed in claim 10 , wherein the keratin and/or keratin polymer-containing substance comprises discarded feathers.

12. The biological hair shape change composition as claimed in claim 1 , wherein a volume ratio of the macromolecular component to the small molecular component in the biological hair shape change composition is 5-10:1.5-3.

13. The biological hair shape change composition as claimed in claim 1 , further comprising additional water.

14. A biological hair shape change kit, comprising:
a macromolecular component, comprising:
a protease belonging to the class of alkaline proteases;
a small molecular component, comprising:
a peptide with reduction activity;
an alkali agent component; and
at least one packaging container for containing the macromolecular component, the small molecular component and the alkali agent component,
wherein both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium,
wherein molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa, and
wherein the biological hair shape change kit is used in the form of a mixture of the macromolecular component, the small molecular component and the alkali agent component.

15. The biological hair shape change kit as claimed in claim 14 , wherein the protease belonging to the class of alkaline proteases comprises alkaline protease, keratinase or a combination thereof.

16. The biological hair shape change kit as claimed in claim 14 , wherein the length of the peptide with reduction activity is 5-30 amino acids.

17. The biological hair shape change kit as claimed in claim 14 , wherein the peptide with reduction activity comprises at least one of the following peptides:
(a) a peptide comprising the amino acid sequence of SEQ ID NO. 1;
(b) a peptide comprising the amino acid sequence of SEQ ID NO. 2;
(c) a peptide comprising the amino acid sequence of SEQ ID NO. 3;
(d) a peptide comprising the amino acid sequence of SEQ ID NO. 4;
(e) a peptide comprising the amino acid sequence of SEQ ID NO. 5;
(f) a peptide comprising the amino acid sequence of SEQ ID NO. 6;
(g) a peptide comprising the amino acid sequence of SEQ ID NO. 7;
(h) a peptide comprising the amino acid sequence of SEQ ID NO. 8;
(i) a peptide comprising the amino acid sequence of SEQ ID NO. 9; and
(j) a peptide comprising the amino acid sequence of SEQ ID NO. 10.

18. The biological hair shape change kit as claimed in claim 14 , wherein the alkali agent component comprises a plant-derived alkali agent and/or a chemical synthesis-derived alkali agent.

19. The biological hair shape change kit as claimed in claim 18 , wherein the plant-derived alkali agent comprises at least one of the following plant-derived alkali agents:
a water extract of coffee grounds, a water extract of tea stems, and a water extract of mulberry leaves.

20. The biological hair shape change kit as claimed in claim 14 , wherein the Bacillus licheniformis comprises Bacillus licheniformis BCRC 14353, Bacillus licheniformis GI_5E-1 of which the deposit number is CCTCC M 20211045, or a combination thereof.

21. The biological hair shape change kit as claimed in claim 14 , wherein the keratin and/or keratin polymer-containing medium comprise a keratin and/or keratin polymer-containing substance, and the keratin and/or keratin polymer-containing substance comprises feathers, hair, hooves, claws and/or horns of animals.

22. The biological hair shape change kit as claimed in claim 21 , wherein a content of the keratin and/or keratin polymer-containing substance in the keratin and/or keratin polymer-containing medium is 0.01-20 g/L.

23. The biological hair shape change kit as claimed in claim 21 , wherein the keratin and/or keratin polymer-containing substance comprises discarded feat

Assignees

• Ind Tech Res Inst

Inventors

• Han Yin-Lung
• Cheng Chieh-Lun
• Fan kai-chun
• Gao Pei-Jyuan
• Chen Bo-Han

Classifications

• A61K8/985

  Skin or skin outgrowth, e.g. hair, nails · CPC title

• A61K2800/78

  Enzyme modulators, e.g. Enzyme agonists · CPC title

• A61K2800/882

  Mixing prior to application · CPC title

• A61K2800/85

  Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine · CPC title

• A61Q5/04

  Preparations for permanent waving or straightening the hair · CPC title