Leave-on oral care compositions

Patent metadata

Field	Value
Publication number	US-12194129-B2
Application number	US-202318530533-A
Country	US
Kind code	B2
Filing date	Dec 6, 2023
Priority date	Jun 14, 2019
Publication date	Jan 14, 2025
Grant date	Jan 14, 2025

Abstract

Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Leave-on oral care compositions can comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer, and an additional polymer.

First claim

What is claimed is:

1. A leave-on oral care composition comprising:
a) from about 0.1% to about 10%, by weight of the composition, of a hyaluronic acid or a salt thereof, wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 2,000,000 Daltons;
b) from about 0.5% to about 10%, by weight of the composition, of a polyacrylic acid;
c) from about 0.5% to about 10%, by weight of the composition, of an additional polymer, wherein the additional polymer does not include an anionic cellulose; and
d) from about 30% to about 75%, by weight of the composition, of total water content.

2. The leave-on oral care composition of claim 1 , wherein the hyaluronic acid is present in an amount of from about 0.1% to about 5%, by weight of the composition.

3. The leave-on oral care composition of claim 1 , wherein the polyacrylic acid is present in the amount of from about 0.5% to about 5%, by weight of the composition.

4. The leave-on oral care composition of claim 1 , further comprising from about 0.01% to about 5%, by weight of the composition, of allantoin.

5. The leave-on oral care composition of claim 1 , wherein the additional polymer is selected from the group consisting of natural gum, linear sulfated polysaccharide, nonionic cellulose derivative, co-polymers of maleic anhydride with methyl vinyl ether, polyvinyl pyrrolidine, and combinations thereof.

6. The leave-on oral care composition of claim 5 , wherein the additional polymer is present in the amount of from about 0.2% to about 10%, by weight of the composition.

7. The leave-on oral care composition of claim 5 , wherein the additional polymer is selected from the group consisting of xanthan gum, carrageenan, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, polyvinyl pyrrolidine, and combinations thereof.

8. The leave-on oral care composition of claim 1 , further comprising a polyol selected from the group consisting of glycerol, erythritol, xylitol, sorbitol, mannitol, and combinations thereof.

9. The leave-on oral care composition of claim 8 , wherein the polyol is present in the amount of from about 1% to about 30%, by weight of the composition.

10. The leave-on oral care composition of claim 1 , further comprising a vitamin selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.

11. The leave-on oral care composition of claim 1 , wherein the total water content is from about 40% to about 75%, by weight of the composition.

12. The leave-on oral care composition of claim 1 , wherein the oral care composition is in a gel form.

13. The leave-on oral care composition of claim 1 , wherein the oral care composition is substantially free of abrasives.

14. A method of improving gum health of a subject, the method comprising the steps of applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue a duration of time of from about 1 minute to about 1000 minutes.

15. The method of claim 14 , wherein the applying step is conducted as a last step of an oral hygiene regimen.

16. The method of claim 14 , wherein the leave-on oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

17. A method of improving gum health of a subject, the method comprising the steps of:
(a) brushing teeth of the subject with an antibacterial toothpaste; and
(b) subsequently, applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue for a duration of time of from about 1 minute to about 1000 minutes.

18. The method of claim 17 , wherein the oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

19. A kit comprising a toothpaste and the leave-on oral care composition of claim 1 .

20. A kit comprising the leave-on oral care composition of claim 1 and a delivery carrier, wherein the delivery carrier comprises strip, film of material, dental tray, aligner, sponge material, applicator, or mixtures thereof.

Assignees

• Procter & Gamble

Inventors

• Strand Ross
• Su Yang
• Shi Yunming
• Shanmugam Thanigaivel
• Wang Guannan
• Li Xiaoxiao

Classifications

• A61K8/4946

  Imidazoles or their condensed derivatives, e.g. benzimidazoles · CPC title

• A61K2800/87

  Application Devices; Containers; Packaging · CPC title

• A61K2800/30

  Characterized by the absence of a particular group of ingredients · CPC title

• A61K8/8147

  Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers · CPC title

• A61K2800/92

  Oral administration · CPC title