Neuromodulation of pharyngeal nerves to treat diseases
US-2024366279-A1 · Nov 7, 2024 · US
US12178492B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12178492-B2 |
| Application number | US-202218045569-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 11, 2022 |
| Priority date | Aug 13, 2019 |
| Publication date | Dec 31, 2024 |
| Grant date | Dec 31, 2024 |
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A controller for a cooled radiofrequency ablation system is configured to sequentially activate a plurality of pump assemblies with a pump activation time delay between the activation of each of the plurality of pump assemblies, measure a temperature drop delay time for each of a plurality of cooled radiofrequency ablation probes, map each respective pump assembly of the plurality of pump assemblies to a corresponding cooled radiofrequency ablation probe of the plurality of cooled radiofrequency ablation probes based on the temperature drop delay time and an activation time of each of the plurality of pump assemblies, and confirm the mapping of each respective pump assembly to the corresponding cooled radiofrequency ablation probe by comparing, for each of the plurality of cooled radiofrequency probes, the measured temperature drop delay time to an expected temperature drop delay time.
Opening claim text (preview).
What is claimed is: 1. A controller for a cooled radiofrequency ablation system, the controller comprising a non-transitory memory having instructions stored thereon that, when executed by a processor, cause the controller to: sequentially activate a plurality of pump assemblies with a pump activation time delay between the activation of each of the plurality of pump assemblies; measure a temperature drop delay time for each of a plurality of cooled radiofrequency ablation probes, wherein the temperature drop delay time is an amount of time for a temperature decrease to be detected at a tip of each respective cooled radiofrequency ablation probe of the plurality of cooled radiofrequency ablation probes after activation of a first pump assembly of the plurality of pump assemblies; map each respective pump assembly of the plurality of pump assemblies to a corresponding cooled radiofrequency ablation probe of the plurality of cooled radiofrequency ablation probes based on the temperature drop delay time and an activation time of each of the plurality of pump assemblies; and confirm the mapping of each respective pump assembly to the corresponding cooled radiofrequency ablation probe by comparing, for each of the plurality of cooled radiofrequency probes, the measured temperature drop delay time to an expected temperature drop delay time, wherein the expected temperature drop delay time is calculated based on the measured temperature drop delay time for a corresponding one of the plurality of pump assemblies and the pump activation time delay. 2. The controller of claim 1 , wherein each of the plurality of cooled radiofrequency probes comprises a thermocouple at its tip, the instructions further causing the controller to monitor a temperature at the tip of each of the plurality of cooled radiofrequency probes to detect the temperature decrease. 3. The controller of claim 1 , wherein the temperature drop delay time is measured between the time of activation of the first pump assembly and the time cooling fluid reaches the tip of the first radiofrequency ablation probe exhibiting a temperature decrease of at least 0.5 degrees Celsius. 4. The controller of claim 1 , wherein the instructions further cause the controller to detect the presence of two or more cooled radiofrequency ablation probes daisy-chained to a single pump assembly. 5. The controller of claim 1 , wherein each of the plurality of pump assemblies is mapped to one of the plurality of radiofrequency ablation probes that experiences the temperature drop delay time soonest after the activation time of each respective pump assembly of the plurality of pump assemblies. 6. The controller of claim 1 , wherein the pump activation time delay ranges from 5 seconds to 10 seconds. 7. The controller of claim 1 , wherein each of the plurality of cooled radiofrequency probes is electrically and fluidically coupled to the controller via respective cable-tubing assemblies, and wherein the cable-tubing assemblies comprise an electrical cable and a dual-lumen fluid tubing. 8. The controller of claim 7 , wherein a volumetric flow rate, path length, and cross-section area of the dual fluid tubing is equal for all of the plurality of cooled radiofrequency probes. 9. The controller of claim 5 , wherein mapping each cooled radiofrequency probe to a respective pump assembly connected thereto further comprises: detecting whether two or more of the plurality of cooled radiofrequency probes are daisy-chained together and therefore associated with one pump assembly of the plurality of pump assemblies by determining whether the temperature drop delay time for one or more of the plurality of cooled radiofrequency probes does not match a known value in sequence following the activation of each of the plurality of pump assemblies. 10. A method of mapping a plurality of cooled radiofrequency probes to respective pump assemblies for cooled radiofrequency ablation, the method comprising: sequentially activating each pump assembly of a plurality of pump assemblies; mapping each cooled radiofrequency probe of the a plurality of cooled radiofrequency probes to a respective pump assembly connected thereto by measuring a temperature drop delay time for each cooled radio frequency probe, wherein the temperature drop delay time is the amount of time for cooling fluid to reach a tip of the cooled radiofrequency ablation probe and initiate a temperature decrease at the tip of the cooled radiofrequency ablation probe after activation of a first pump assembly of the plurality of pump assemblies; and confirming the mapping of each cooled radiofrequency probe to the respective pump assembly by comparing the measured temperature drop delay time to an expected temperature drop delay time for each cooled radiofrequency probe, wherein expected temperature drop delay time is calculated from a recorded activation time of each cooled radiofrequency probe. 11. The method of claim 10 , wherein there is a pump activation time delay between the activation of each pump assembly. 12. The method of claim 11 , wherein the pump activation time delay ranges from 5 seconds to 10 seconds. 13. The method of claim 10 , wherein each radiofrequency probe comprises a thermocouple at the tip of the probe configured to measure the temperature at the tip of the probe, the method further comprising measuring the temperature at the tip of each of the radiofrequency probes. 14. The method of claim 13 , wherein the temperature drop delay time is measured between the time of activation of the first pump assembly and the time cooling fluid reaches the tip of the first radiofrequency ablation probe exhibiting a temperature decrease of at least 0.5 degrees Celsius. 15. The method of claim 10 , wherein each pump assembly is mapped to the radiofrequency ablation probe that measures the temperature drop delay time soonest after the recorded activation time of each pump assembly. 16. The method of claim 10 , wherein the plurality of pump assemblies comprises from two to four pump assemblies, further wherein the plurality of cooled radiofrequency probes comprises from two to four cooled radiofrequency ablation probes. 17. The method of claim 10 , wherein mapping each cooled radiofrequency probe to a respective pump assembly connected thereto further comprises: detecting whether two or more of the plurality of cooled radiofrequency probes are daisy-chained together and therefore associated with one pump assembly of the plurality of pump assemblies by determining whether the temperature drop delay time for one or more of the plurality of cooled radiofrequency probes does not match a known value in sequence following the activation of each of the plurality of pump assemblies. 18. A non-transitory computer readable medium having instructions stored thereon that, when executed by a processor, cause a device to: sequentially activate each pump assembly of a plurality of pump assemblies; map each cooled radiofrequency probe of the a plurality of cooled radiofrequency probes to a respective pump assembly connected thereto by measuring a temperature drop delay time for each cooled radio frequency probe, wherein the temperature drop delay time is the amount of time for cooling fluid to reach a tip of the cooled radiofrequency ablation probe and initiate a temperature decrease at the tip of the cooled radiofrequency ablation probe after activation of a first pump assembly of the plurality of pump assemblies; and confirm the mapping of each cooled radiofrequency probe to the respective pump assembly b
Probes or electrodes therefor · CPC title
Temperature · CPC title
measured by a thermocouple · CPC title
by passing a current through the tissue to be heated, e.g. high-frequency current · CPC title
Characteristics of handpieces or probes · CPC title
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