Powdered thickener maintaining its extensional properties when reconstituted and for promoting safe swallowing by individuals with dysphagia

Patent metadata

Field	Value
Publication number	US-12178228-B2
Application number	US-201816620083-A
Country	US
Kind code	B2
Filing date	Jun 7, 2018
Priority date	Jun 7, 2017
Publication date	Dec 31, 2024
Grant date	Dec 31, 2024

Abstract

A thickening powder promotes safe swallowing of a composition by an individual with dysphagia and can be used in methods of treating dysphagia, promoting safe swallowing of a composition, and mitigating a risk of aspiration during swallowing of a composition. The powder contains beta-glucan and maltodextrin in an amount that is neutral toward or enhances the extensional properties of the composition. Optionally the thickening powder can also include a low molecular weight carbohydrate such as sucrose or lactose. The powder can be diluted in a liquid comprising at least one of water or milk to form at least a portion of a composition such as a nutritional product and to improve the cohesiveness of the composition.

First claim

The invention is claimed as follows:

1. A method of treating a swallowing disorder in an individual having the swallowing disorder, the method comprising administering to the individual a composition comprising:
beta-glucan; and
maltodextrin,
the composition having a shear viscosity of about 1 mPas to about 200 mPas when measured at a shear rate of 50 s −1 and a relaxation time determined by a Capillary Breakup Extensional Rheometry (CaBER) experiment of about 10 to about 2,000 milliseconds (ms) at a temperature of 20° C.,
wherein the composition comprises the maltodextrin and the beta-glucan in a weight ratio of about 10:1 to about 300:1.

2. The method of claim 1 , wherein the composition is a liquid.

3. The method of claim 1 , wherein the maltodextrin is maltodextrin DE 20.

4. The method of claim 1 , wherein the composition further comprises at least one of a sucrose or lactose.

Assignees

• Nestle Sa

Inventors

• Marchesini Giulia
• Engmann Jan
• Widmer Christoph
• Dutter Thibaut

Classifications

• A61K9/145

  with organic compounds · CPC title

• A61K9/0095

  Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches (A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006) · CPC title

• A23L2/39 Primary

  Dry compositions · CPC title

• A23L29/212

  Starch; Modified starch; Starch derivatives, e.g. esters or ethers (containing starch hydrolysates, e.g. dextrin, A23L29/30) · CPC title

• Y02A50/30

  Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change · CPC title